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Eticyclidine (PCE, CI-400) is a dissociativeanesthetic drug with hallucinogenic effects. It is similar in effects to phencyclidine but is slightly more potent. PCE was developed by Parke-Davis in the 1970s and evaluated for anesthetic potential under the code name CI-400,[2] but research into PCE was not continued after the development of ketamine, a similar drug with more favourable properties.[3] PCE is slightly more potent than PCP and has similar effects,[medical citation needed] but its unpleasant taste and tendency to cause nausea made it less accepted by users.[citation needed] Due to its similarity in effects to PCP, PCE was placed into the Schedule 1 list of illegal drugs in the 1970s, although it was only briefly abused in the 1970s and 1980s and is now little known.
^Levy L, Cameron DE, Aitken RC (March 1960). "Observation on two psychotomimetic drugs of piperidine derivation--CI 395 (sernyl) and CI 400". The American Journal of Psychiatry. 116 (9): 843–4. doi:10.1176/ajp.116.9.843. PMID14416411.
^Kalir A, Edery H, Pelah Z, Balderman D, Porath G (May 1969). "1-Phenycycloalkylamine derivatives. II. Synthesis and pharmacological activity". Journal of Medicinal Chemistry. 12 (3): 473–7. doi:10.1021/jm00303a030. PMID4977945.
This page was last edited on 4 February 2024, at 22:01