Delirant drug
 | |
| Identifiers | |
|---|---|
| |
| CAS Number | |
| PubChem CID | |
| ChemSpider | |
| ChEMBL | |
| Chemical and physical data | |
| Formula | C19H23NO3 |
| Molar mass | 313.397 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
CAR-302,282 (302282, NSC-263548, α-(3-Methylbut-1-yn-3-enyl)mandelic acid 1-methyl-4-piperidyl ester) is an anticholinergic deliriant drug,[1][2] invented under contract to Edgewood Arsenal in the 1960s. It is a potent incapacitating agent with an ED50 of 1.2μg/kg and a high central to peripheral effects ratio, and a relatively short duration of action compared to other similar drugs of around 6-10 hours. Despite its favorable properties it was relatively little researched compared to more high profile compounds from the series such as EA-3167 and EA-3580.[3]
See also
References
- ^ Baumgold J, Abood LG, Aronstam R (March 1977). "Studies on the relationship of binding affinity to psychoactive and anticholingergic potency of a group of psychotomimetic glycolates". Brain Research. 124 (2): 331–40. doi:10.1016/0006-8993(77)90889-7. PMID 843950. S2CID 35326203.
- ^ US 4465834, Baum BM, Stange H, "Anticholinergic Drugs.", issued 14 August 1984
- ^ Ketchum JS (2006). Chemical Warfare Secrets Almost Forgotten. A Personal Story of Medical Testing of Army Volunteers with Incapacitating Chemical Agents During the Cold War. ChemBooks Inc. p. 320-326. ISBN 978-1-4243-0080-8.
| mAChRsTooltip Muscarinic acetylcholine receptors |
| ||||
|---|---|---|---|---|---|
| Precursors (and prodrugs) | |||||
 | This hallucinogen-related article is a stub. You can help Wikipedia by expanding it. |
This page was last edited on 7 April 2023, at 21:26