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From Wikipedia, the free encyclopedia

CP 55,244
Identifiers
  • (2S,4S,4aS,6R,8aR)-6-(Hydroxymethyl)-4-[2-hydroxy-4-(2-methyloctan-2-yl)phenyl]-1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalen-2-ol
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC26H42O3
Molar mass402.619 g·mol−1
3D model (JSmol)
  • CCCCCCC(C)(C)c1ccc(c(c1)O)[C@H]2C[C@H](C[C@@H]3[C@@H]2C[C@@H](CC3)CO)O
  • InChI=1S/C26H42O3/c1-4-5-6-7-12-26(2,3)20-10-11-22(25(29)15-20)24-16-21(28)14-19-9-8-18(17-27)13-23(19)24/h10-11,15,18-19,21,23-24,27-29H,4-9,12-14,16-17H2,1-3H3/t18-,19-,21+,23+,24-/m1/s1
  • Key:ZAELPWSCABXXAB-QXASVXAKSA-N
  (verify)

CP 55,244 is a chemical compound which is a cannabinoid receptor agonist. It has analgesic effects and is used in scientific research. It is an extremely potent CB1 full agonist with a Ki of 0.21 nM, making it more potent than the commonly used full agonist HU-210.[1][2]

See also

References

  1. ^ Melvin LS, Milne GM, Johnson MR, Wilken GH, Howlett AC (November 1995). "Structure-activity relationships defining the ACD-tricyclic cannabinoids: cannabinoid receptor binding and analgesic activity". Drug Design and Discovery. 13 (2): 155–66. PMID 8872458.
  2. ^ Griffin G, Wray EJ, Martin BR, Abood ME (October 1999). "Cannabinoid agonists and antagonists discriminated by receptor binding in rat cerebellum". British Journal of Pharmacology. 128 (3): 684–8. doi:10.1038/sj.bjp.0702806. PMC 1571656. PMID 10516649.
This page was last edited on 1 May 2024, at 08:02
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