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Trestolone enanthate

From Wikipedia, the free encyclopedia

Trestolone enanthate
Clinical data
Other namesTrestolone 17β-enanthate; MENT enanthate; 7α-Methyl-19-nortestosterone 17β-enanthate; 7α-Methylestr-4-en-17β-ol-3-one 17β-enanthate
Drug classAndrogen; Anabolic steroid; Androgen ester
Identifiers
  • (7R,8R,9S,10R,13S,14S,17S)-7,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl heptanoate
CAS Number
UNII
Chemical and physical data
FormulaC26H40O3
Molar mass400.603 g·mol−1
3D model (JSmol)
  • CCCCCCC(O[C@]1(CC[C@]2([C@@]3([C@@H](CC4=CC(CC[C@@]4([C@]3(CC[C@@]21C)[H])[H])=O)C)[H])[H])[H])=O
  • InChI=1S/C26H40O3/c1-4-5-6-7-8-24(28)29-23-12-11-22-25-17(2)15-18-16-19(27)9-10-20(18)21(25)13-14-26(22,23)3/h16-17,20-23,25H,4-15H2,1-3H3/t17-,20+,21-,22+,23+,25-,26+/m1/s1
  • Key:YHLLSSBURKVUEG-YFGHHJRWSA-N

Trestolone enanthate, also known as 7α-methyl-19-nortestosterone 17β-enanthate (MENT enanthate), is an androgen and anabolic steroid (AAS) and progestogen which was never marketed.[1][2] It is an androgen ester; specifically, it is the C17β enanthate (heptanoate) ester of trestolone (7α-methylestr-4-en-17β-ol-3-one).[1][2] Trestolone enanthate has low affinity for sex hormone-binding globulin (SHBG), similarly to testosterone enanthate.[1]

See also

References

  1. ^ a b c Cunningham GR, Tindall DJ, Lobl TJ, Campbell JA, Means AR (September 1981). "Steroid structural requirements for high affinity binding to human sex steroid binding protein (SBP)". Steroids. 38 (3): 243–62. doi:10.1016/0039-128X(81)90061-1. PMID 7197818. S2CID 2702353.
  2. ^ a b Bursi R, Grootenhuis A, van der Louw J, Verhagen J, de Gooyer M, Jacobs P, Leysen D (March 2003). "Structure-activity relationship study of human liver microsomes-catalyzed hydrolysis rate of ester prodrugs of MENT by comparative molecular field analysis (CoMFA)". Steroids. 68 (3): 213–220. doi:10.1016/S0039-128X(02)00186-1. PMID 12628684. S2CID 32309966.



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This page was last edited on 30 December 2023, at 12:39
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