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Methylclostebol

From Wikipedia, the free encyclopedia

Methylclostebol
Clinical data
Other namesChloromethyltestosterone; CMT; 4-Chloro-17α-methyltestosterone; 4-Chloro-17α-methylandrost-4-en-17β-ol-3-one
Routes of
administration		Oral
Legal status
Legal status
Identifiers
  • (8R,9S,10R,13S,14S,17S)-4-Chloro-17-hydroxy-10,13,17-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
CAS Number
PubChem CID
ChemSpider
UNII
ChEBI
Chemical and physical data
FormulaC20H29ClO2
Molar mass336.90 g·mol−1
3D model (JSmol)
  • C[C@]12CCC(=O)C(=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@]4(C)O)C)Cl
  • InChI=1S/C20H29ClO2/c1-18-9-8-16(22)17(21)15(18)5-4-12-13(18)6-10-19(2)14(12)7-11-20(19,3)23/h12-14,23H,4-11H2,1-3H3/t12-,13+,14+,18-,19+,20+/m1/s1
  • Key:SOMOGWLYTLQJGT-XMUHMHRVSA-N

Methylclostebol, also known as 4-chloro-17α-methyltestosterone or as 4-chloro-17α-methylandrost-4-en-17β-ol-3-one, is a synthetic, orally active anabolic-androgenic steroid (AAS) and designer steroid that has been sold on the Internet as a "dietary supplement",[1][2] but it has never been studied for medical use.[3] It is the 17α-alkylated variant of clostebol (4-chlorotestosterone).[4]

Rahnema, Crosnoe, and Kim (2015) reported that German athletes used methylclostebol as a performance enhancing drug in the 1960s and 1970s, but this has not been substantiated.[3] The compound is listed as a banned anabolic agent by the World Anti-Doping Agency.[5]

See also

References

  1. ^ Rahnema CD, Crosnoe LE, Kim ED (March 2015). "Designer steroids - over-the-counter supplements and their androgenic component: review of an increasing problem". Andrology. 3 (2): 150–155. doi:10.1111/andr.307. PMID 25684733. S2CID 6999218.
  2. ^ Pope HG, Wood RI, Rogol A, Nyberg F, Bowers L, Bhasin S (June 2014). "Adverse health consequences of performance-enhancing drugs: an Endocrine Society scientific statement". Endocrine Reviews. 35 (3): 341–375. doi:10.1210/er.2013-1058. PMC 4026349. PMID 24423981.
  3. ^ a b Rahnema CD, Crosnoe LE, Kim ED (March 2015). "Designer steroids - over-the-counter supplements and their androgenic component: review of an increasing problem". Andrology. 3 (2): 150–155. doi:10.1111/andr.307. PMID 25684733. S2CID 6999218.
  4. ^ Lootens L, Van Eenoo P, Pozo Mendoza OJ, Meulemans P, Leroux-Roels G, Delbeke F (2010). "Application of in vivo urinary steroid detection in uPA+/+-SCID chimeric mice.". 28th Cologne workshop on Dope Analysis (Manfred Donike workshop). Vol. 18. pp. 52–61.
  5. ^ "World Anti-Doping Code: International Standard Prohibited List" (PDF). January 2017.
This page was last edited on 11 November 2023, at 17:46
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