![]() | |
Clinical data | |
---|---|
Other names | Gestonorone; 17α-Hydroxy-19-norprogesterone; 17α-Hydroxy-19-norpregn-4-ene-3,20-dione |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.016.708 |
Chemical and physical data | |
Formula | C20H28O3 |
Molar mass | 316.441 g·mol−1 |
3D model (JSmol) | |
| |
|
Gestronol (BAN), also known as gestonorone, as well as 17α-hydroxy-19-norprogesterone or 17α-hydroxy-19-norpregn-4-ene-3,20-dione, is a progestin of the 19-norprogesterone and 17α-hydroxyprogesterone groups which was never marketed.[1][2][3] The C17α caproate ester of gestronol, gestonorone caproate (gestronol hexanoate), in contrast, has been marketed.[1][2][3]
Gestronol shows relatively low affinity for the progesterone receptor, only about 12.5% of that of progesterone and about 2.5% of that of 19-norprogesterone in one assay.[4] On the other hand, gestronol had far higher affinity than 17α-hydroxyprogesterone, which showed less than 0.1% of the affinity of progesterone for the progesterone receptor.[4]
YouTube Encyclopedic
-
1/3Views:5 911502 8582 299
-
Progest 10 mg tablet Bangla | Progest 10 mg tablet এর কাজ কি?
-
পিরিয়ড দেরীতে হওয়ার ১৫টি বিশেষ কারণ । 15 Reasons for Missed or Irregular Periods in Bangla
-
ANOVA - Two-Way, Multi-Way, Interaction (part 3 of 4)
Transcription
See also
References
- ^ a b Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 595–. ISBN 978-1-4757-2085-3.
- ^ a b Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 132–. ISBN 978-94-011-4439-1.
- ^ a b Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 1357–. ISBN 978-3-88763-075-1.
- ^ a b Botella J, Duc I, Delansorne R, Paris J, Lahlou B (December 1990). "Structure-activity and structure-affinity relationships of 19-nor-progesterone derivatives in rat uterus". Journal of Endocrinological Investigation. 13 (11): 905–910. doi:10.1007/BF03349652. PMID 2090671. S2CID 37429648.
![](/s/i/modif.png)