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Keratin 15 is a protein that in humans is encoded by the KRT15gene.[5][6] It has also been referred to as cytokeratin 15, K1CO and KRTB.
Keratin 15 is a type I cytokeratin. It is well-expressed in the basal layer of complex epithelia. However, acral keratinocytes express little to no keratin 15.[7]
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Barletta C, Batticane N, Ragusa RM, Leube R, Peschle C, Romano V (1990). "Subchromosomal localization of two human cytokeratin genes (KRT4 and KRT15) by in situ hybridization". Cytogenetics and Cell Genetics. 54 (3–4): 148–150. doi:10.1159/000132979. PMID1702379.
Blumenberg M, Savtchenko ES (1986). "Linkage of human keratin genes". Cytogenetics and Cell Genetics. 42 (1–2): 65–71. doi:10.1159/000132253. PMID2424675.
Bader BL, Jahn L, Franke WW (December 1988). "Low level expression of cytokeratins 8, 18 and 19 in vascular smooth muscle cells of human umbilical cord and in cultured cells derived therefrom, with an analysis of the chromosomal locus containing the cytokeratin 19 gene". European Journal of Cell Biology. 47 (2): 300–319. PMID2468493.
Romano V, Bosco P, Rocchi M, Costa G, Leube RE, Franke WW, Romeo G (1988). "Chromosomal assignments of human type I and type II cytokeratin genes to different chromosomes". Cytogenetics and Cell Genetics. 48 (3): 148–151. doi:10.1159/000132612. PMID2466616.
Werner S, Munz B (January 2000). "Suppression of keratin 15 expression by transforming growth factor beta in vitro and by cutaneous injury in vivo". Experimental Cell Research. 254 (1): 80–90. doi:10.1006/excr.1999.4726. PMID10623468.
Whittock NV, Eady RA, McGrath JA (January 2000). "Genomic organization and amplification of the human keratin 15 and keratin 19 genes". Biochemical and Biophysical Research Communications. 267 (1): 462–465. doi:10.1006/bbrc.1999.1966. PMID10623642.
Al-Refu K, Goodfield M (May 2009). "Hair follicle stem cells in the pathogenesis of the scarring process in cutaneous lupus erythematosus". Autoimmunity Reviews. 8 (6): 474–477. doi:10.1016/j.autrev.2008.12.015. PMID19162247.
This page was last edited on 7 November 2023, at 05:34