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Keratin, type I cuticular Ha1 is a protein that in humans is encoded by the KRT31gene.[5][6][7]
Function
The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription.[7]
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Fink P, Rogers MA, Korge B, Winter H, Schweizer J (Oct 1995). "A cDNA encoding the human type I hair keratin hHal". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1264 (1): 12–4. doi:10.1016/0167-4781(95)00122-w. PMID7578244.
Yu J, Yu DW, Checkla DM, Freedberg IM, Bertolino AP (Jul 1993). "Human hair keratins". The Journal of Investigative Dermatology. 101 (1 Suppl): 56S–59S. doi:10.1111/1523-1747.ep12362635 (inactive 2024-04-03). PMID7686952.{{cite journal}}: CS1 maint: DOI inactive as of April 2024 (link)
Dhouailly D, Xu C, Manabe M, Schermer A, Sun TT (Mar 1989). "Expression of hair-related keratins in a soft epithelium: subpopulations of human and mouse dorsal tongue keratinocytes express keratin markers for hair-, skin- and esophageal-types of differentiation". Experimental Cell Research. 181 (1): 141–58. doi:10.1016/0014-4827(89)90189-4. PMID2465162.
Bowden PE, Hainey S, Parker G, Hodgins MB (Jul 1994). "Sequence and expression of human hair keratin genes". Journal of Dermatological Science. 7 Suppl: S152-63. doi:10.1016/0923-1811(94)90046-9. PMID7528047.
Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3 (1): 89. doi:10.1038/msb4100134. PMC1847948. PMID17353931.