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KIF7

From Wikipedia, the free encyclopedia

KIF7
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesKIF7, ACLS, HLS2, JBTS12, UNQ340, AGBK, kinesin family member 7
External IDsOMIM: 611254 MGI: 1098239 HomoloGene: 72555 GeneCards: KIF7
Orthologs
SpeciesHumanMouse
Entrez

374654

16576

Ensembl

ENSG00000166813

ENSMUSG00000050382

UniProt

Q2M1P5

B7ZNG0

RefSeq (mRNA)

NM_198525

NM_001291222
NM_010626

RefSeq (protein)

NP_940927

n/a

Location (UCSC)Chr 15: 89.61 – 89.66 MbChr 7: 79.35 – 79.37 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Kinesin family member 7 (KIF7), also known as kinesin-4, is a human protein encoded by the gene KIF7. It is part of the kinesin family of motor proteins.

Function

KIF7 depolymerises the growing plus-end of microtubules, and is involved in regulating Hedgehog signalling.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000166813 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000050382 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ He M, Subramanian R, Bangs F, Omelchenko T, Liem KF, Kapoor TM, Anderson KV (July 2014). "The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment". Nature Cell Biology. 16 (7): 663–672. doi:10.1038/ncb2988. PMC 4085576. PMID 24952464.


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This page was last edited on 16 December 2022, at 15:31
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