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Cianopramine

From Wikipedia, the free encyclopedia

Cianopramine
Clinical data
ATC code
  • none
Identifiers
  • 5-[3-(Dimethylamino)propyl]-10,11-dihydro-5H-dibenzo[b,f]azepine-3-carbonitrile
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC20H23N3
Molar mass305.425 g·mol−1
3D model (JSmol)
  • N#Cc1ccc3c(c1)N(c2ccccc2CC3)CCCN(C)C

Cianopramine (INN) (developmental code name Ro 11-2465), also known as 3-cyanoimipramine, is a tricyclic antidepressant related to imipramine that acts as a serotonin reuptake inhibitor[1] and weak serotonin receptor antagonist.[2][3] It was investigated for the treatment of depression but was never marketed.[3]

See also

References

  1. ^ Kenny M, Lenehan TJ, Lambe R, Darragh A, Brick I, Omer LM (1983). "Effects of a single oral dose of 3-cyano-imipramine on serotonin uptake and content of platelets in healthy volunteers". Psychopharmacology. 79 (4): 304–7. doi:10.1007/bf00433406. PMID 6407042. S2CID 3112636.
  2. ^ Pawłowski L, Kwiatek H, Górka Z (1981). "Is Ro 11-2465 (cyan-imipramine) an antagonist of postsynaptic serotonin receptors?". Journal of Neural Transmission. 52 (1–2): 61–72. doi:10.1007/BF01253098. PMID 7288439. S2CID 41042435.
  3. ^ a b Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 270–. ISBN 978-1-4757-2085-3.
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This page was last edited on 5 May 2024, at 00:04
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