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| Clinical data | |
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| Trade names | Vasocon-a |
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| Routes of administration | Topical (nasal, eye drops) |
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| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.001.904 |
| Chemical and physical data | |
| Formula | C17H19N3 |
| Molar mass | 265.360 g·mol−1 |
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Antazoline is a 1st generation antihistamine with anticholinergic properties used to relieve nasal congestion and in eye drops, usually in combination with naphazoline, to relieve the symptoms of allergic conjunctivitis.[1] To treat allergic conjunctivitis, antazoline can be combined in a solution with tetryzoline.[2] The drug is a Histamine H1 receptor antagonist:[3] selectively binding to but not activating the receptor, thereby blocking the actions of endogenous histamine and subsequently leading to the temporary relief of the negative symptoms brought on by histamine.
A large study on people 65 years old or older linked the development of Alzheimer's disease and other forms of dementia to the "higher cumulative" use of first-generation antihistamines, due to their anticholinergic properties.[4]
YouTube Encyclopedic
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Top 4 Dry Eye Treatments Most Doctors Won't Tell You
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Antazol nasal drop | antazol drop এর কাজ কি | xylometazoline nasal drop
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Allergic Conjunctivitis
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Best Eye Allergies Treatment |Naphazoline Eye Drop| Drink/Smoke करने के बाद इस Eye Drop का Use करें।
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افضل قطرة لحساسية العين و الالتهابات
Transcription
References
- ^ Abelson MB, Allansmith MR, Friedlaender MH (August 1980). "Effects of topically applied occular decongestant and antihistamine". American Journal of Ophthalmology. 90 (2): 254–257. doi:10.1016/s0002-9394(14)74864-0. PMID 7425039.
- ^ Castillo M, Scott NW, Mustafa MZ, Mustafa MS, Azuara-Blanco A (June 2015). "Topical antihistamines and mast cell stabilisers for treating seasonal and perennial allergic conjunctivitis". The Cochrane Database of Systematic Reviews. 2015 (6): CD009566. doi:10.1002/14651858.CD009566.pub2. hdl:2164/6048. PMC 10616535. PMID 26028608.
- ^ Noguchi S, Inukai T, Kuno T, Tanaka C (June 1992). "The suppression of olfactory bulbectomy-induced muricide by antidepressants and antihistamines via histamine H1 receptor blocking". Physiology & Behavior. 51 (6): 1123–1127. doi:10.1016/0031-9384(92)90297-f. PMID 1353628. S2CID 29562845.
- ^ Gray SL, Anderson ML, Dublin S, Hanlon JT, Hubbard R, Walker R, et al. (March 2015). "Cumulative use of strong anticholinergics and incident dementia: a prospective cohort study". JAMA Internal Medicine. 175 (3): 401–407. doi:10.1001/jamainternmed.2014.7663. PMC 4358759. PMID 25621434.
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This page was last edited on 5 January 2024, at 05:53