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Hydroxycarteolol

From Wikipedia, the free encyclopedia

Hydroxycarteolol
Clinical data
Other names8-Hydroxycarteolol
ATC code
  • None
Identifiers
  • 8-Hydroxy-5-{2-hydroxy-3-[(2-methyl-2-propanyl)amino]propoxy}-3,4-dihydro-2(1H)-quinolinone
CAS Number
PubChem CID
ChemSpider
ChEBI
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC16H24N2O4
Molar mass308.378 g·mol−1
3D model (JSmol)
  • O=C2Nc1c(O)ccc(OCC(O)CNC(C)(C)C)c1CC2
  • InChI=1S/C16H24N2O4/c1-16(2,3)17-8-10(19)9-22-13-6-5-12(20)15-11(13)4-7-14(21)18-15/h5-6,10,17,19-20H,4,7-9H2,1-3H3,(H,18,21)
  • Key:TVZJLAKRXHGVOK-UHFFFAOYSA-N

Hydroxycarteolol is a beta blocker and metabolite of carteolol.[1][2]

References

  1. ^ Igarashi H, Katsuta Y, Sawa K, Nakazato Y, Kawasaki T (Apr 1990). "A comparison of the opacifying effects of carteolol.HCl and 8-hydroxycarteolol.HCl in the isolated porcine cornea". Fundam Appl Toxicol. 14 (3): 554–559. doi:10.1093/toxsci/14.3.554. PMID 2340982.
  2. ^ Jasper JR, Michel MC, Insel PA (1990). "The beta-adrenoceptor antagonist carteolol and its metabolite 8-hydroxycarteolol have different intrinsic sympathomimetic activities". Br J Clin Pharmacol. 30 (Suppl 1): 109S–111S. doi:10.1111/j.1365-2125.1990.tb05477.x. PMC 1368107. PMID 2176514.


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This page was last edited on 3 December 2022, at 23:07
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