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5-Fluoro-EPT

From Wikipedia, the free encyclopedia

5-Fluoro-EPT
Identifiers
  • N-ethyl-N-[2-(5-fluoro-1H-indol-3-yl)ethyl]propan-1-amine
PubChem CID
Chemical and physical data
FormulaC15H21FN2
Molar mass248.345 g·mol−1
3D model (JSmol)
  • CCCN(CC)CCC1=CNC2=C1C=C(C=C2)F
  • InChI=1S/C15H21FN2/c1-3-8-18(4-2)9-7-12-11-17-15-6-5-13(16)10-14(12)15/h5-6,10-11,17H,3-4,7-9H2,1-2H3
  • Key:QONMHCQBCANXJS-UHFFFAOYSA-N

5-Fluoro-EPT (5F-EPT, 5-fluoro-N-ethyl-N-propyltryptamine) is a psychedelic tryptamine derivative related to drugs such as EPT and 5-MeO-EPT. It acts as a potent full agonist at the 5-HT2A receptor with an EC50 of 5.54 nM and an efficacy of 104% (compared to serotonin). It produces a head-twitch response in animal studies, and is claimed to have antidepressant activity.[1]

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Transcription

See also

References

  1. ^ WO 2021/168082, Kruegel AC, Sporn J, "Specific Tryptamines for use in the Treatment of Mood Disorders.", published 26 August 2021, assigned to Gilgamesh Pharmaceuticals, Inc.. 


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This page was last edited on 3 May 2022, at 16:02
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