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Taniplon

From Wikipedia, the free encyclopedia

Taniplon
Clinical data
ATC code
  • none
Identifiers
  • 3-(5-methoxy-6,7,8,9-tetrahydroimidazo[1,2-a]quinazolin-2-yl)-5-methyl-1,2,4-oxadiazole
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H15N5O2
Molar mass285.307 g·mol−1
3D model (JSmol)
  • CC1=NC(C2=CN3C(N=C(OC)C4=C3CCCC4)=N2)=NO1
  • InChI=1S/C14H15N5O2/c1-8-15-12(18-21-8)10-7-19-11-6-4-3-5-9(11)13(20-2)17-14(19)16-10/h7H,3-6H2,1-2H3 ☒N
  • Key:OYKONKGGKFFMDV-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Taniplon is a nonbenzodiazepine anxiolytic drug from the imidazoquinazoline family of drugs.

Taniplon binds strongly to benzodiazepine sites on the GABAA receptor and has similar anxiolytic effects in animals, but with less sedative or muscle relaxant action.[1]

References

  1. ^ Tully WR, Gardner CR, Gillespie RJ, Westwood R (July 1991). "2-(oxadiazolyl)- and 2-(thiazolyl)imidazo[1,2-a]pyrimidines as agonists and inverse agonists at benzodiazepine receptors". Journal of Medicinal Chemistry. 34 (7): 2060–7. doi:10.1021/jm00111a021. PMID 1648620.
This page was last edited on 23 January 2023, at 11:47
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