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Reposal

From Wikipedia, the free encyclopedia

Reposal
Clinical data
Other namesReposamal, 5-Ethyl-5-(bicyclo(3.2.1)octenyl)barbituric acid
ATC code
Identifiers
  • 5-bicyclo[3.2.1]oct-2-en-3-yl-5-ethylpyrimidine-2,4,6(1H,3H,5H)-trione
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H18N2O3
Molar mass262.309 g·mol−1
3D model (JSmol)
  • O=C1NC(=O)NC(=O)C1(CC)C=3C[C@H]2C[C@H](CC2)C=3
  • InChI=1S/C14H18N2O3/c1-2-14(11(17)15-13(19)16-12(14)18)10-6-8-3-4-9(5-8)7-10/h6,8-9H,2-5,7H2,1H3,(H2,15,16,17,18,19)/t8-,9+/m0/s1 checkY
  • Key:MKELYWOVSPVORM-DTWKUNHWSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Reposal is a barbiturate derivative invented in the 1960s in Denmark. It has sedative, hypnotic and anticonvulsant properties, and was used primarily for the treatment of insomnia.[1][2][3]

References

  1. ^ Kessing SV, Tarding F, Thomsen AC (December 1963). "Reposal, A New Hypnotic. I. Pharmacodynamic Activity". Ugeskrift for Laeger (in Danish). 125: 1735–8. PMID 14103836.
  2. ^ Kessing SV, Tarding F, Thomsen AC (December 1963). "Reposal, A New Hypnotic. Ii. Clinical Effects". Ugeskrift for Laeger (in Danish). 125: 1739–41. PMID 14103837.
  3. ^ Nielsen P, Tarding F (1968). "The metabolic fate of 5-(bicyclo-3,2,1,-oct-2-en-2-yl)-5-ethyl barbituric acid, (Reposal)". Acta Pharmacologica et Toxicologica. 26 (6): 521–30. doi:10.1111/j.1600-0773.1968.tb00471.x. PMID 5756387.
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This page was last edited on 4 February 2024, at 11:25
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