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Revospirone

From Wikipedia, the free encyclopedia

Revospirone
Clinical data
ATC code
  • none
Identifiers
  • 1,1-dioxo-2-[3-(4-pyrimidin-2-ylpiperazin-1-yl)propyl]-1,2-benzothiazol-3-one
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC18H21N5O3S
Molar mass387.46 g·mol−1

Revospirone (Bay Vq 7813) is an azapirone drug which was patented as a veterinary tranquilizer but was never marketed.[1] It acts as a selective 5-HT1A receptor partial agonist.[2] Similarly to other azapirones such as buspirone, revospirone produces 1-(2-pyrimidinyl)piperazine (1-PP) as an active metabolite.[2] As a result, it also acts as an α2-adrenergic receptor antagonist to an extent.[2]

References

  1. ^ Macdonald F (1997). Dictionary of Pharmacological Agents. CRC Press. p. 1744. ISBN 978-0-412-46630-4. Retrieved 13 May 2012.
  2. ^ a b c Löscher W, Witte U, Fredow G, Traber J, Glaser T (September 1990). "The behavioural responses to 8-OH-DPAT, ipsapirone and the novel 5-HT1A receptor agonist Bay Vq 7813 in the pig". Naunyn-Schmiedeberg's Archives of Pharmacology. 342 (3): 271–7. doi:10.1007/bf00169437. PMID 2149168. S2CID 24769939.


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This page was last edited on 22 January 2023, at 23:56
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