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DPI-221

From Wikipedia, the free encyclopedia

DPI-221
Identifiers
  • 4-((αS)-α-((2S,5R)-2,5-dimethyl-4-(3-fluorobenzyl)-1-piperazinyl)benzyl)-N,N-diethylbenzamide
PubChem CID
ChemSpider
Chemical and physical data
FormulaC31H38FN3O
Molar mass487.651
3D model (JSmol)
  • O=C(N(CC)CC)c1ccc(cc1)[C@@H](N3C[C@H](N(Cc2cc(F)ccc2)C[C@@H]3C)C)c4ccccc4
  • InChI=1S/C31H38FN3O/c1-5-33(6-2)31(36)28-17-15-27(16-18-28)30(26-12-8-7-9-13-26)35-21-23(3)34(20-24(35)4)22-25-11-10-14-29(32)19-25/h7-19,23-24,30H,5-6,20-22H2,1-4H3/t23-,24+,30+/m1/s1
  • Key:KEXJLZMJVOTFOY-QEGDFHJFSA-N
  (verify)

DPI-221 is an opioid drug that is used in scientific research. It is a highly selective agonist for the δ-opioid receptor, which produces fewer convulsions than most drugs from this family.[1]

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Transcription

References

  1. ^ Holt JD, Watson MJ, Chang JP, O'Neill SJ, Wei K, Pendergast W, et al. (November 2005). "DPI-221 [4-((alpha-s)-alpha-((2s,5r)-2,5-dimethyl-4-(3-fluorobenzyl)-1-piperazinyl)benzyl)-N,N-diethylbenzamide]: a novel nonpeptide delta receptor agonist producing increased micturition interval in normal rats". The Journal of Pharmacology and Experimental Therapeutics. 315 (2): 601–8. doi:10.1124/jpet.105.090498. PMID 16020629. S2CID 97486165.


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This page was last edited on 8 February 2024, at 13:57
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