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Fluocortin

From Wikipedia, the free encyclopedia

Fluocortin
Clinical data
Other names6α-fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20,21-trione
ATC code
Pharmacokinetic data
Bioavailability80% i.v.
Elimination half-life1.3 hr.
Identifiers
  • 2-[(6S,8S,9S,10R,11S,13S,14S,16R,17S)-6-Fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoacetic acid
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.046.698 Edit this at Wikidata
Chemical and physical data
FormulaC22H27FO5
Molar mass390.451 g·mol−1
3D model (JSmol)
  • C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@H]3[C@H](C[C@@]2([C@H]1C(=O)C(=O)O)C)O)C)F
  • InChI=1S/C22H27FO5/c1-10-6-13-12-8-15(23)14-7-11(24)4-5-21(14,2)18(12)16(25)9-22(13,3)17(10)19(26)20(27)28/h4-5,7,10,12-13,15-18,25H,6,8-9H2,1-3H3,(H,27,28)/t10-,12+,13+,15+,16+,17-,18-,21+,22+/m1/s1
  • Key:PUWHHWCHAVXSIG-NCLPIGKXSA-N
  (verify)

Fluocortin is a corticosteroid. It is similar to fluocortolone, but with one more keto group.[1]

References

  1. ^ Täuber U, Haack D, Nieuweboer B, Kloss G, Vecsei P, Wendt H (January 1984). "The pharmacokinetics of fluocortolone and prednisolone after intravenous and oral administration". International Journal of Clinical Pharmacology, Therapy, and Toxicology. 22 (1): 48–55. PMID 6698661.
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This page was last edited on 23 April 2022, at 10:07
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