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Amelometasone

From Wikipedia, the free encyclopedia

Amelometasone
Clinical data
Other namesTS-410; 21-O-Methyl-17-O-propionylbetamethasone; Betamethasone 17-propionate 21-methoxide; 9α-Fluoro-11β,17α-dihydroxy-21-methoxy-16β-methylpregna-1,4-diene-3,20-dione 17-propionate
Drug classCorticosteroid; Glucocorticoid
Identifiers
  • [(8S,9R,10S,11S,13S,14S,16S,17R)-9-Fluoro-11-hydroxy-17-(2-methoxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC26H35FO6
Molar mass462.558 g·mol−1
3D model (JSmol)
  • CCC(=O)O[C@@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)C)C(=O)COC
  • InChI=1S/C26H35FO6/c1-6-22(31)33-26(21(30)14-32-5)15(2)11-19-18-8-7-16-12-17(28)9-10-23(16,3)25(18,27)20(29)13-24(19,26)4/h9-10,12,15,18-20,29H,6-8,11,13-14H2,1-5H3/t15-,18-,19-,20-,23-,24-,25-,26-/m0/s1
  • Key:ZMYGOSBRLPSJNB-SOMXGXJRSA-N

Amelometasone (developmental code name TS-410) is a synthetic glucocorticoid corticosteroid which was never marketed.[1][2]

References

  1. ^ Shepard TH, Lemire RJ (2004). Catalog of Teratogenic Agents. JHU Press. pp. 20–. ISBN 978-0-8018-7953-1.
  2. ^ "The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances" (PDF). International Nonproprietary Names (INN) Programme. World Health Organization. 2013.



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