Desoximetasone

Desoximetasone

Clinical data
Trade names	Topicort, Emcor, Desacort
AHFS/Drugs.com	Monograph
MedlinePlus	a605026
Routes of administration	Topical
ATC code	D07AC03 (WHO) D07XC02 (WHO) (combinations)
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name (8S,9S,10S,11S,13S,14S,16R,17S)-9-Fluoro-11- hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl- 7,8,11,12,14,15,16,17-octahydro-6H- cyclopenta[a]phenanthren-3-one
CAS Number	382-67-2 Y
PubChem CID	5311067
IUPHAR/BPS	7067
DrugBank	DB00547 Y
ChemSpider	21117768 Y
UNII	4E07GXB7AU
KEGG	D03697 Y
ChEMBL	ChEMBL1766 N
CompTox Dashboard (EPA)	DTXSID3045647
ECHA InfoCard	100.006.224
Chemical and physical data
Formula	C22H29FO4
Molar mass	376.468 g·mol−1
3D model (JSmol)	Interactive image
SMILES OCC(=O)[C@H]3[C@H](C)CC2C4CC/C1=C/C(=O)\C=C/[C@]1(C)[C@@]4(F)[C@@H](O)C[C@@]23C
InChI InChI=1S/C22H29FO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-21(13,3)22(15,23)18(27)10-20(16,2)19(12)17(26)11-24/h6-7,9,12,15-16,18-19,24,27H,4-5,8,10-11H2,1-3H3/t12-,15?,16?,18+,19-,20+,21+,22+/m1/s1 Y Key:VWVSBHGCDBMOOT-ZIKVJHDZSA-N Y
NY (what is this?)  (verify)

Desoximetasone is a medication belonging to the family of medications known as topical corticosteroids. It is used for the relief of various skin conditions, including rashes. It helps to reduce redness, itching, and irritation.^[1] Desoximetasone is a synthetic corticosteroid, a class of primarily synthetic steroids used as anti-inflammatory and anti-pruritic agents.

Three brand name products are available (availability depending on country):

• Topicort Emollient Cream (0.25% desoximetasone)
• Topicort LP Emollient Cream (0.05% desoximetasone)
• Topisolone Cream (0.25% desoximetasone)

Usage

When using desoximetasone, some of the medication may be absorbed through the skin and into the bloodstream. Too much absorption can lead to unwanted side effects elsewhere in the body. Large amounts of desoximetasone should be avoided over large areas. It should not be used for extended periods of time. Treated areas should not be covered with airtight dressings such as plastic wrap or adhesive bandages.^[1] Children may absorb more medication than adults do. Desoximetasone is for use only on the skin and should be kept out of the eyes.

Desoximetasone can also be used to treat some types of psoriasis.

See also

• Clobetasol propionate
• Dexamethasone

References

External links

• Topicort general info
• Topicort usage info

This page was last edited on 17 January 2024, at 17:34