Acephate

Acephate

Names
Preferred IUPAC name Dimethyl N-acetylphosphoramidothioate
Identifiers
CAS Number	30560-19-1 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:34520 Y
ChEMBL	ChEMBL2133249 N
ChemSpider	1905 Y
ECHA InfoCard	100.045.659
KEGG	C14426 Y
PubChem CID	1982
RTECS number	TB4760000
UNII	3Y417O444D Y
CompTox Dashboard (EPA)	DTXSID8023846
InChI InChI=1S/C4H10NO3PS/c1-4(6)5-9(7,8-2)10-3/h1-3H3,(H,5,6,7) Y Key: YASYVMFAVPKPKE-UHFFFAOYSA-N Y InChI=1/C4H10NO3PS/c1-4(6)5-9(7,8-2)10-3/h1-3H3,(H,5,6,7) Key: YASYVMFAVPKPKE-UHFFFAOYAG
SMILES O=C(NP(=O)(OC)SC)C
Properties
Chemical formula	C4H10NO3PS
Molar mass	183.16 g·mol−1
Appearance	colourless to white solid
Density	1.35 g/cm3
Melting point	88–90 °C (190–194 °F; 361–363 K)
Solubility in water	79 g/100 mL
Solubility	very soluble in acetone soluble in ethanol
Vapor pressure	2x10−6 mmHg
Pharmacology
Legal status	AU: S6 (Poison)
Hazards
GHS labelling:[1]
Pictograms
Signal word	Warning
Hazard statements	H302
Precautionary statements	P264, P270, P301+P312, P330, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

Acephate is an organophosphate foliar and soil insecticide of moderate persistence with residual systemic activity of about 10–15 days at the recommended use rate. It is used primarily for control of aphids, including resistant species, in vegetables (e.g. potatoes, carrots, greenhouse tomatoes, and lettuce) and in horticulture (e.g. on roses and greenhouse ornamentals). It also controls leaf miners, caterpillars, sawflies, thrips, and spider mites in the previously stated crops as well as turf, and forestry. By direct application to mounds, it is effective in destroying imported fire ants.

Acephate is sold as a soluble powder, as emulsifiable concentrates, as pressurized aerosol, and in tree injection systems and granular formulations.

As of 2012, the EPA no longer allows the usage of acephate on green beans grown in the United States.^[2]

Toxicology

It is considered non-phytotoxic on many crop plants. Acephate and its primary metabolite, methamidophos, are toxic to Heliothis spp. that are considered resistant to other organophosphate insecticides. Acephate emits toxic fumes of various oxides of phosphorus, nitrogen, and sulfur when heated to decomposition. Symptoms of exposure to acephate include a slight irritation of eyes and skin.

The U.S. annually uses 4–5 million pounds of acephate.^{[citation needed]}

The EU classifies Acephate as an Annex III substance, meaning that it meets the requirements to be considered a health and environmental hazard. ^[3]

References

• U.S. EPA Office of Pesticide Programs.
• Extension Toxicology Network. Pesticide Information Profiles.
• Cooperative Extension Offices of Cornell University, Oregon State University, the University of Idaho, and the University of California at Davis.
• Institute for Environmental Toxicology, Michigan State University.

External links

• Acephate General Fact Sheet - National Pesticide Information Center
• Acephate Pesticide Information Profile - Extension Toxicology Network
• EPA Acephate Reregistration Eligibility Decision
• Acephate in the Pesticide Properties DataBase (PPDB)
• Lepitect - Soil injected Pesticide for Ornamental Use

This page was last edited on 6 May 2024, at 00:14