To install click the Add extension button. That's it.

The source code for the WIKI 2 extension is being checked by specialists of the Mozilla Foundation, Google, and Apple. You could also do it yourself at any point in time.

How to transfigure the Wikipedia

Would you like Wikipedia to always look as professional and up-to-date? We have created a browser extension. It will enhance any encyclopedic page you visit with the magic of the WIKI 2 technology.

Try it — you can delete it anytime.

Install in 5 seconds
4,5
Kelly Slayton
Congratulations on this excellent venture… what a great idea!
Alexander Grigorievskiy
I use WIKI 2 every day and almost forgot how the original Wikipedia looks like.
Live Statistics
English Articles
Improved in 24 Hours
Added in 24 Hours
What we do. Every page goes through several hundred of perfecting techniques; in live mode. Quite the same Wikipedia. Just better.
Great Wikipedia has got greater.
.
Leo
Newton
Brights
Milds

Ipidacrine

From Wikipedia, the free encyclopedia

Ipidacrine
Clinical data
Trade namesNeiromidin
Other namesAmiridine; NIK-247
ATC code
Legal status
Legal status
  • US: Unscheduled Not FDA approved
Identifiers
  • 2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-amine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.201.385 Edit this at Wikidata
Chemical and physical data
FormulaC12H16N2
Molar mass188.274 g·mol−1
3D model (JSmol)
  • C1CCc2c(c(c3c(n2)CCC3)N)C1
  • InChI=1S/C12H16N2/c13-12-8-4-1-2-6-10(8)14-11-7-3-5-9(11)12/h1-7H2,(H2,13,14)
  • Key:YLUSMKAJIQOXPV-UHFFFAOYSA-N

Ipidacrine (Neiromidin) is a drug first synthesized by the National Research Center for Biologically Active Compounds in the Russian Federation. This compound is a modification of the older drug tacrine (Cognex).[1]

Ipidacrine is a reversible acetylcholinesterase inhibitor used in memory disorders of different origins.[2][3][4]

Ipidacrine directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels. Ipidacrine enhances not only choline, but also adrenaline, serotonin, histamine, and oxytocin effects on smooth muscle.[5]

YouTube Encyclopedic

  • 1/2
    Views:
    284 489
    4 520 481
  • Phenibut: What You Need To Know
  • Холестерин: диета не нужна? Таблетки от холестерина - пить или нет.

Transcription

References

  1. ^ Kojima J, Onodera K, Ozeki M, Nakayarna K (1998). "Ipidacrine (NIK-247): A Review of Multiple Mechanisms as an Antidementia Agent". CNS Drug Reviews. 4 (3): 247–259. doi:10.1111/j.1527-3458.1998.tb00067.x.
  2. ^ Damulin IV, Stepkina DA, Lokshina AB (2011). "[Neuromidin in mixed vascular and Alzheimer's dementia]". Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova. 111 (2): 40–3. PMID 21350422.
  3. ^ Pustokhanova LV, Morozova EM (2011). "[Cognitive disorders in the early rehabilitation period of ischemic stroke and possibilities of their treatment with neuromidin]". Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova. 111 (4 Pt 2): 23–7. PMID 23120773.
  4. ^ Onodera K, Kojima J, Wachi M (April 1998). "Ipidacrine (NIK-247), a novel antidementia, rapidly enters the brain and improves scopolamine-induced amnesia in rats during the Morris water maze task". Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. 18 (2): 33–7. PMID 9656230.
  5. ^ "Neiromidin Product Information". Archived from the original on 2013-06-13. Retrieved 2013-05-30.
This page was last edited on 9 February 2024, at 02:30
Basis of this page is in Wikipedia. Text is available under the CC BY-SA 3.0 Unported License. Non-text media are available under their specified licenses. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc. WIKI 2 is an independent company and has no affiliation with Wikimedia Foundation.
Contact WIKI 2
Introduction
Terms of Service
Privacy Policy