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Mucin-5AC(MUC-5AC) is a protein that in humans is encoded by the MUC5ACgene.[5][6][7]
MUC-5AC is a large gel-forming glycoprotein. In the respiratory tract it protects against infection by binding to inhaled pathogens that are subsequently removed by mucociliary clearance. Overproduction of MUC-5AC can contribute to diseases such as asthma and chronic obstructive pulmonary disease,[8] and has also been associated with greater protection against influenza infection.[9]
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^van de Bovenkamp JH, Hau CM, Strous GJ, Buller HA, Dekker J, Einerhand AW (Jun 1998). "Molecular cloning of human gastric mucin MUC5AC reveals conserved cysteine-rich D-domains and a putative leucine zipper motif". Biochem Biophys Res Commun. 245 (3): 853–9. doi:10.1006/bbrc.1998.8535. PMID9588204.
^Samsuzzaman M, Uddin MS, Shah MA, Mathew B (August 2019). "Natural inhibitors on airway mucin: Molecular insight into the therapeutic potential targeting MUC5AC expression and production". Life Sciences. 231: 116485. doi:10.1016/j.lfs.2019.05.041. PMID31116959. S2CID162182150.
This page was last edited on 22 December 2023, at 16:10