The leukotriene (LT) receptors are G protein-coupled receptors that bind and are activated by the leukotrienes. They include the following proteins:
- Leukotriene B4 receptors (BLTRs) – bind to and are activated by LTB4:
- BLT1 (Leukotriene B4 receptor 1) – LTB4R
- BLT2 (Leukotriene B4 receptor 2) – LTB4R2
- Cysteinyl leukotriene receptors (CysLTRs) – bind to and are activated by LTC4, LTD4, and LTE4:
- CysLT1 (Cysteinyl leukotriene receptor 1) – CYSLTR1
- CysLT2 (Cysteinyl leukotriene receptor 2) – CYSLTR2
The recently elucidated CysLTE, represented by GPR99/OXGR1, may constitute a third CysLTR.[1]
YouTube Encyclopedic
-
1/5Views:13 92019 96726 7082 6766 041
-
Montelukast
-
Drugs for Asthma Treatment
-
Histamine, Prostaglandin, Leukotrienes, Bradkinin, PGE2 LTB4 Chemotactic Factors
-
Biochemistry Help: Leukotrienes, synthesis
-
Asthma Drugs - Muscarinic Antagonists (Ipratropium)
Transcription
See also
References
- ^ Kanaoka Y, Maekawa A, Austen KF (2013). "Identification of GPR99 protein as a potential third cysteinyl leukotriene receptor with a preference for leukotriene E4 ligand". J. Biol. Chem. 288 (16): 10967–72. doi:10.1074/jbc.C113.453704. PMC 3630866. PMID 23504326.
External links
- IUPHAR GPCR Database – Leukotriene receptors
- Leukotriene+Receptors at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
 | This biochemistry article is a stub. You can help Wikipedia by expanding it. |
This page was last edited on 3 May 2022, at 16:40