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From Wikipedia, the free encyclopedia

GPR179
Identifiers
AliasesGPR179, CSNB1E, GPR158L, GPR158L1, G protein-coupled receptor 179
External IDsOMIM: 614515 MGI: 2443409 HomoloGene: 34917 GeneCards: GPR179
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001004334

NM_001081220
NM_175453

RefSeq (protein)

NP_001004334

NP_001074689

Location (UCSC)Chr 17: 38.32 – 38.34 MbChr 11: 97.22 – 97.24 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Probable G-protein coupled receptor 179 is a protein that in humans is encoded by the GPR179 gene.[5]

Clinical relevance

Mutations in this gene have been associated to cases of congenital stationary Night Blindness.[6]

References

  1. ^ a b c ENSG00000277399 GRCh38: Ensembl release 89: ENSG00000276469, ENSG00000277399 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000070337 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: GPR179 G protein-coupled receptor 179".
  6. ^ Audo I, Bujakowska K, Orhan E, Poloschek CM, Defoort-Dhellemmes S, Drumare I, Kohl S, Luu TD, Lecompte O, Zrenner E, Lancelot ME, Antonio A, Germain A, Michiels C, Audier C, Letexier M, Saraiva JP, Leroy BP, Munier FL, Mohand-Saïd S, Lorenz B, Friedburg C, Preising M, Kellner U, Renner AB, Moskova-Doumanova V, Berger W, Wissinger B, Hamel CP, Schorderet DF, De Baere E, Sharon D, Banin E, Jacobson SG, Bonneau D, Zanlonghi X, Le Meur G, Casteels I, Koenekoop R, Long VW, Meire F, Prescott K, de Ravel T, Simmons I, Nguyen H, Dollfus H, Poch O, Léveillard T, Nguyen-Ba-Charvet K, Sahel JA, Bhattacharya SS, Zeitz C (Feb 10, 2012). "Whole-Exome Sequencing Identifies Mutations in GPR179 Leading to Autosomal-Recessive Complete Congenital Stationary Night Blindness". American Journal of Human Genetics. 90 (2): 321–30. doi:10.1016/j.ajhg.2011.12.007. PMC 3276675. PMID 22325361.

Further reading

  • Bjarnadóttir TK, Fredriksson R, Schiöth HB (2006). "The gene repertoire and the common evolutionary history of glutamate, pheromone (V2R), taste(1) and other related G protein-coupled receptors". Gene. 362: 70–84. doi:10.1016/j.gene.2005.07.029. PMID 16229975.
This page was last edited on 19 June 2022, at 20:12
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