In biochemistry, an endoribonuclease is a class of enzyme which is a type of ribonuclease (an RNA cleaver), itself a type of endonuclease (a nucleotide cleaver). It cleaves either single-stranded or double-stranded RNA, depending on the enzyme. Example includes both single proteins such as RNase III, RNase A, RNase T1, RNase T2 and RNase H and also complexes of proteins with RNA such as RNase P and the RNA-induced silencing complex. Further examples include endoribonuclease XendoU found in frogs (Xenopus).
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Mod-04 Lec-14 Regulation of tRNA and 5s rRNA synthesis by RNA Polymerase III
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External links
- Endoribonucleases at the U.S. National Library of Medicine Medical Subject Headings (MeSH)