Sulfathiourea

Sulfathiourea
Clinical data

Other names	(4-aminophenyl)sulfonylthiourea
ATC code	J01EB08 (WHO)
Identifiers
IUPAC name 4-amino-N-(aminocarbonothioyl)benzenesulfonamide
CAS Number	515-49-1
PubChem CID	3000579
ChemSpider	2272143^Y
UNII	MXF9G4I1V5
KEGG	D07239^Y
ChEBI	CHEBI:131723
CompTox Dashboard (EPA)	DTXSID4046868
ECHA InfoCard	100.007.457
Chemical and physical data
Formula	C₇H₉N₃O₂S₂
Molar mass	231.29 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=S(=O)(c1ccc(N)cc1)NC(=S)N
InChI InChI=1S/C7H9N3O2S2/c8-5-1-3-6(4-2-5)14(11,12)10-7(9)13/h1-4H,8H2,(H3,9,10,13)^Y Key:UEMLYRZWLVXWRU-UHFFFAOYSA-N^Y
(verify)

Sulfathiourea is a sulfonamide antibacterial.^[1]

References

^ Schoog M (November 1953). "[Sulfathiourea, chemistry, pharmacology and clinical aspects]". Zeitschrift für Haut- und Geschlechtskrankheiten (in German). 15 (10): 315–8. PMID 13137202.

Antifolates
(inhibit bacterial
purine metabolism,
thereby inhibiting
DNA and RNA
synthesis)

Short-acting	Sulfaisodimidine Sulfamethizole Sulfadimidine Sulfapyridine (Sulfasalazine) Sulfafurazole (Acetyl sulfisoxazole) Sulfanilamide Prontosil Sulfathiazole (Phthalylsulfathiazole, Succinylsulfathiazole) Sulfathiourea
Intermediate-acting	Sulfamethoxazole Sulfadiazine^# Sulfamoxole
Long-acting	Sulfadimethoxine Sulfadoxine Sulfalene Sulfametomidine Sulfametoxydiazine Sulfamethoxypyridazine Sulfaperin Sulfamerazine Sulfaphenazole Sulfamazone
Other/ungrouped	Mafenide Sulfacetamide Sulfaclozine Sulfadicramide Sulfaguanidine Sulfametrole Sulfanitran

Combinations

Other DHPS inhibitors

2nd generation	Ciprofloxacin^# Ofloxacin Enoxacin^‡ Fleroxacin^‡ Lomefloxacin^‡ Nadifloxacin^‡ Norfloxacin^‡ Pefloxacin^‡ Rufloxacin^‡
3rd generation	Levofloxacin^# Balofloxacin^‡ Grepafloxacin^‡ Pazufloxacin^‡ Sparfloxacin^‡ Temafloxacin^‡ Tosufloxacin^‡
4th generation	Besifloxacin Delafloxacin Gatifloxacin Finafloxacin Gemifloxacin Moxifloxacin^# Clinafloxacin^† Garenoxacin^‡ Prulifloxacin^‡ Sitafloxacin^‡ Trovafloxacin^‡/Alatrofloxacin^‡
Veterinary	Danofloxacin Difloxacin Enrofloxacin Ibafloxacin Marbofloxacin Orbifloxacin Pradofloxacin Sarafloxacin^‡

Newer non-fluorinated

Related (DG)

Nitroimidazole derivatives	Metronidazole^# Ornidazole Secnidazole Tinidazole
Nitrofuran derivatives	Furazolidone^‡ Nifuroxazide Nifurtoinol Nifurzide Nitrofurantoin^# Nitrofurazone

RNA synthesis

Rifamycins/ RNA polymerase	Rifampicin^# Rifabutin^# Rifapentine^# Rifaximin Rifalazil^§
Lipiarmycins	Fidaxomicin

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This page was last edited on 29 January 2023, at 20:27