Pyrrolidonyl-β-naphthylamide

Pyrrolidonyl-β-naphthylamide
Names

IUPAC name N¹-(Naphthalen-2-yl)-5-oxo-L-prolinamide
Systematic IUPAC name (2S)-N-(Naphthalen-2-yl)-5-oxopyrrolidine-2-carboxamide
Other names Pyrrolidonyl-beta-naphthylamide
Identifiers
CAS Number	22155-91-5^N
3D model (JSmol)	Interactive image
ChemSpider	81932^Y
ECHA InfoCard	100.040.721
PubChem CID	90745
UNII	6G5U8A2YEH^Y
CompTox Dashboard (EPA)	DTXSID10944800
InChI InChI=1S/C15H14N2O2/c18-14-8-7-13(17-14)15(19)16-12-6-5-10-3-1-2-4-11(10)9-12/h1-6,9,13H,7-8H2,(H,16,19)(H,17,18)^Y Key: BZEPQNMASTUAMY-UHFFFAOYSA-N^Y InChI=1/C15H14N2O2/c18-14-8-7-13(17-14)15(19)16-12-6-5-10-3-1-2-4-11(10)9-12/h1-6,9,13H,7-8H2,(H,16,19)(H,17,18) Key: BZEPQNMASTUAMY-UHFFFAOYAS
SMILES O=C(Nc2cc1ccccc1cc2)C3NC(=O)CC3
Properties
Chemical formula	C₁₅H₁₄N₂O₂
Molar mass	254.289 g·mol⁻¹
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references

Pyrrolidonyl-β-naphthylamide (PYR) is a molecule used in microbiology to detect the presence of pyrrolidonyl peptidase.^[1] In the presence of bacteria with pyrrolidonyl peptidase, it is broken down to pyroglutamic acid and 2-naphthylamine. To detect this process, p-dimethylaminocinnamaldehyde is added and a change to a pink color can then be detected.

References

^ Oberhofer, Thomas R. (1986). "Value of the l-pyrrolidonyl-β-naphthylamide hydrolysis test for identification of select gram-positive cocci". Diagnostic Microbiology and Infectious Disease. 4: 43–47. doi:10.1016/0732-8893(86)90055-6.

Isolation techniques	Asepsis Streak plate Selective media
Cultures by body site	Blood culture Genital culture Sputum culture Throat culture Urine culture Wound culture
Cultures by organism	Bacterial culture Fungal culture Viral culture

Identification
and testing

Manual testing: basic techniques	Colonial morphology Hemolysis Staining Gram stain Acid-fast stain Giemsa stain India ink stain Ziehl–Neelsen stain Wet prep Rapid tests Oxidase Catalase Indole PYR
Manual testing: biochemical and immunologic tests	ALA test Amino acid decarboxylase test Bile solubility test CAMP test Citrate test Coagulase test DNAse test IMViC KOH test Methyl red test Nitrite test ONPG test Oxidative/fermentation glucose test Phenylalanine deaminase test Reverse CAMP test Salt tolerance test Sulfide indole motility test Triple sugar iron test Urease test rapid Voges–Proskauer test X and V factor test Bacitracin susceptibility test Optochin susceptibility test Novobiocin susceptibility test Lancefield grouping RPR test
Automated and point-of-care testing	Analytical profile index MALDI-TOF Polymerase chain reaction VITEK system Rapid strep test Monospot test
Antibiotic susceptibility testing	Beta-lactamase test Disk diffusion test Etest McFarland standards Minimum inhibitory concentration

Equipment

This article about a heterocyclic compound is a stub. You can help Wikipedia by expanding it.

This page was last edited on 5 April 2024, at 01:06