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Insulin like 6

From Wikipedia, the free encyclopedia

INSL6
Identifiers
AliasesINSL6, RIF1, insulin like 6
External IDsOMIM: 606414 MGI: 1351595 HomoloGene: 5197 GeneCards: INSL6
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_007179

NM_013754

RefSeq (protein)

NP_009110

NP_038782

Location (UCSC)Chr 9: 5.12 – 5.19 MbChr 19: 29.3 – 29.3 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Insulin like 6 is a protein that in humans is encoded by the INSL6 gene. [5]

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Transcription

Function

The protein encoded by this gene contains a classical signature of the insulin superfamily and is significantly similar to relaxin and relaxin-like factor. This gene is preferentially expressed in testis. Its expression in testis is restricted to interstitial cells surrounding seminiferous tubules, which suggests a role in sperm development and fertilization.

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000120210 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000050957 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Insulin like 6". Retrieved 2016-02-25.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


This page was last edited on 29 January 2021, at 19:44
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