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Dupracetam

From Wikipedia, the free encyclopedia

Dupracetam
Clinical data
ATC code
  • none
Legal status
Legal status
  • In general: unscheduled
Identifiers
  • 2-(2-oxopyrrolidin-1-yl)-N'-[2-(2-oxopyrrolidin-1-yl)acetyl]acetohydrazide
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.056.279 Edit this at Wikidata
Chemical and physical data
FormulaC12H18N4O4
Molar mass282.300 g·mol−1
3D model (JSmol)
  • C1CC(=O)N(C1)CC(=O)NNC(=O)CN2CCCC2=O
  • InChI=1S/C12H18N4O4/c17-9(7-15-5-1-3-11(15)19)13-14-10(18)8-16-6-2-4-12(16)20/h1-8H2,(H,13,17)(H,14,18) ☒N
  • Key:YPUPYVWSTBYCBY-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Dupracetam is a nootropic drug from the racetam family.[1][2]

One of its metabolites, 1-Methylhydantoin, displays renal toxicity in high doses.[3]

See also

References

  1. ^ Dell HD, Jacobi H, Kamp R, Kurz J, Wünsche C (August 1981). "[1-Methylhydantoin, an unexpected metabolite of the intelligence-affecting substance dupracetam (author's transl)]". Archiv der Pharmazie (in German). 314 (8): 697–702. doi:10.1002/ardp.19813140808. PMID 7294979. S2CID 95603731.
  2. ^ Hall ED, Von Voigtlander PF (November 1987). "Facilitatory effects of piracetam on excitability of motor nerve terminals and neuromuscular transmission". Neuropharmacology. 26 (11): 1573–1579. doi:10.1016/0028-3908(87)90003-7. PMID 2829047. S2CID 7759558.
  3. ^ Yang B, Liu D, Li CZ, Liu FY, Peng YM, Jiang YS (2007). "1-Methylhydantoin cytotoxicity on renal proximal tubular cells in vitro". Renal Failure. 29 (8): 1025–1029. doi:10.1080/08860220701641272. PMID 18067051. S2CID 26843776.
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This page was last edited on 20 November 2023, at 13:51
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