Body fluid

Body fluids, bodily fluids, or biofluids, sometimes body liquids, are liquids within the body of an organism.^[1] In lean healthy adult men, the total body water is about 60% (60–67%) of the total body weight; it is usually slightly lower in women (52–55%).^[2]^[3] The exact percentage of fluid relative to body weight is inversely proportional to the percentage of body fat. A lean 70 kg (150 lb) man, for example, has about 42 (42–47) liters of water in his body.

The total body of water is divided into fluid compartments,^[1] between the intracellular fluid compartment (also called space, or volume) and the extracellular fluid (ECF) compartment (space, volume) in a two-to-one ratio: 28 (28–32) liters are inside cells and 14 (14–15) liters are outside cells.

The ECF compartment is divided into the interstitial fluid volume – the fluid outside both the cells and the blood vessels – and the intravascular volume (also called the vascular volume and blood plasma volume) – the fluid inside the blood vessels – in a three-to-one ratio: the interstitial fluid volume is about 12 liters; the vascular volume is about 4 liters.

The interstitial fluid compartment is divided into the lymphatic fluid compartment – about 2/3, or 8 (6–10) liters, and the transcellular fluid compartment (the remaining 1/3, or about 4 liters).^[4]

The vascular volume is divided into the venous volume and the arterial volume; and the arterial volume has a conceptually useful but unmeasurable subcompartment called the effective arterial blood volume.^[5]

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Compartments by location

intracellular fluid (ICF), which consist of cytosol and fluids in the cell nucleus^[6]
Extracellular fluid
- Intravascular fluid (blood plasma)
- Interstitial fluid
- Lymphatic fluid (sometimes included in interstitial fluid)
- Transcellular fluid

Health

Body fluid is the term most often used in medical and health contexts. Modern medical, public health, and personal hygiene practices treat body fluids as potentially unclean. This is because they can be vectors for infectious diseases, such as sexually transmitted diseases or blood-borne diseases. Universal precautions and safer sex practices try to avoid exchanges of body fluids. Body fluids can be analyzed in medical laboratory in order to find microbes, inflammation, cancers, etc.^{[citation needed]}

Clinical samples

Clinical samples are generally defined as non-infectious human or animal materials including blood, saliva, excreta, body tissue and tissue fluids, and also FDA-approved pharmaceuticals that are blood products.^[7] In medical contexts, it is a specimen taken for diagnostic examination or evaluation, and for identification of disease or condition.^[8]

Sampling

Methods of sampling of body fluids include:^{[citation needed]}

Blood sampling for any blood test, in turn including:
- Arterial blood sampling, such as radial artery puncture
- Venous blood sampling, also called venipuncture
Lumbar puncture to sample cerebrospinal fluid
Paracentesis to sample peritoneal fluid
Thoracocentesis to sample pleural fluid
Amniocentesis to sample amniotic fluid

References

^ ^a ^b "body fluid". Taber's online – Taber's medical dictionary. Archived from the original on 2021-06-21. Retrieved 2021-06-22.
^ "The water in you". Howard Perlman. December 2016.
^ Lote, Christopher J. Principles of Renal Physiology, 5th edition. Springer. p. 2.
^ Santambrogio, Laura (2018). "The Lymphatic Fluid". International Review of Cell and Molecular Biology. 337: 111–133. doi:10.1016/bs.ircmb.2017.12.002. ISBN 9780128151952. PMID 29551158.
^ Vesely, David L (2013). "Natriuretic Hormones". Seldin and Giebisch's the Kidney: 1241–1281. doi:10.1016/B978-0-12-381462-3.00037-9. ISBN 9780123814623.
^ Liachovitzky, Carlos (2015). "Human Anatomy and Physiology Preparatory Course" (pdf). CUNY Bronx Community College. CUNY Academic Works. p. 69. Archived from the original on 2017-08-23. Retrieved 2021-06-22.
^ Packaging Guidelines for Clinical Samples - Retrieved 7 August 2014.
^ specimen - The Free Dictionary. Retrieved 7 August 2014

External links

De Luca LA, Menani JV, Johnson AK (2014). Neurobiology of Body Fluid Homeostasis: Transduction and Integration. Boca Raton: CRC Press/Taylor & Francis. ISBN 9781466506930.

This page was last edited on 25 January 2024, at 19:41

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