60S ribosomal protein L37a

RPL37A
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4UG0, 4V6X, 5AJ0, 3J92, 4UJE, 4UJD, 4D67, 4V5Z, 4UJC, 4D5Y
Identifiers
Aliases	RPL37A, L37A, ribosomal protein L37a
External IDs	OMIM: 613314; MGI: 98068; HomoloGene: 47964; GeneCards: RPL37A; OMA:RPL37A - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q35 Start 216,498,825 bp[1] End 216,579,180 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 C3 Start 72,750,449 bp[2] End 72,752,972 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in lactiferous duct cerebellar vermis caput epididymis parietal pleura nipple endothelial cell superficial temporal artery pericardium visceral pleura corpus epididymis Top expressed in yolk sac lip morula superior frontal gyrus entorhinal cortex spermatocyte superior surface of tongue spermatid gallbladder corneal stroma More reference expression data BioGPS More reference expression data
Gene ontology Molecular function structural constituent of ribosome metal ion binding protein binding RNA binding Cellular component cytosol ribosome focal adhesion intracellular anatomical structure cytosolic large ribosomal subunit extracellular exosome nucleus Biological process viral transcription SRP-dependent cotranslational protein targeting to membrane translational initiation nuclear-transcribed mRNA catabolic process, nonsense-mediated decay protein biosynthesis rRNA processing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6168 19981 Ensembl ENSG00000197756 ENSMUSG00000046330 UniProt P61513 P61514 RefSeq (mRNA) NM_000998 NM_009084 RefSeq (protein) NP_000989 NP_033110 Location (UCSC) Chr 2: 216.5 – 216.58 Mb Chr 1: 72.75 – 72.75 Mb PubMed search [3] [4]
Wikidata
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60S ribosomal protein L37a is a protein that in humans is encoded by the RPL37A gene.^[5][6]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L37AE family of ribosomal proteins. It is located in the cytoplasm. The protein contains a C4-type zinc finger-like domain. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[6]

References

Further reading

External links

• Overview of all the structural information available in the PDB for UniProt: P61513 (Human 60S ribosomal protein L37a) at the PDBe-KB.

This article on a gene on human chromosome 2 is a stub. You can help Wikipedia by expanding it.

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This page was last edited on 11 September 2023, at 19:54