Pons

Pons
Pons in the brainstem
Anteroinferior view of the medulla oblongata and pons
Details
Part of	Brain stem
Artery	Pontine arteries
Vein	Transverse and lateral pontine veins
Identifiers
MeSH	D011149
NeuroNames	547
NeuroLex ID	birnlex_733
TA98	A14.1.03.010
TA2	5921
FMA	67943
Anatomical terms of neuroanatomy [edit on Wikidata]

The pons (pl.: pontes; from Latin pons, "bridge", from Proto-Indo-European *pónteh₁s, “path, road”, from *pent-, “path”. Cognate with Sanskrit पन्था, pánthā-) is part of the brainstem that in humans and other mammals, lies inferior to the midbrain, superior to the medulla oblongata and anterior to the cerebellum.

The pons is also called the pons Varolii ("bridge of Varolius"), after the Italian anatomist and surgeon Costanzo Varolio (1543–75).^[1] This region of the brainstem includes neural pathways and tracts that conduct signals from the brain down to the cerebellum and medulla, and tracts that carry the sensory signals up into the thalamus.^[2]

Structure

The pons in humans measures about 2.5 centimetres (0.98 in) in length.^[2] It is the part of the brainstem situated between the midbrain and the medulla oblongata,^[3] and in front of the cerebellum.^{[citation needed]} The horizontal medullopontine sulcus demarcates the boundary between the pons and medulla oblongata on the ventral aspect of the brainstem, and the roots of cranial nerves VI/VII/VIII emerge from the brainstem along this groove.^[4] The junction of pons, medulla oblongata, and cerebellum forms an angle - the cerebellopontine angle.^[5] The superior pontine sulcus separates the pons from the midbrain.^[6] Posteriorly, the pons curves on either side into a middle cerebellar peduncle.^[3]

The pons can be broadly divided into two parts: the basilar part of the pons (ventral pons),^[7] and the pontine tegmentum (dorsal pons).^[8]

The ventral aspect of the pons faces the clivus, with the pontine cistern intervening between the two structures. The ventral surface of the pons features a midline basilar sulcus along which the basilar artery may or may not course. There is a bulge to either side of the basilar sulcus, created by the pontine nuclei that are interweaved amid the descending fibres within the substance of the pons. The superior cerebellar artery winds around the upper margin of the pons.^[3]

Vasculature

Most of the pons is supplied by the pontine arteries, which arise from the basilar artery. A smaller portion of the pons is supplied by the anterior and posterior inferior cerebellar arteries.

Development

During embryonic development, the metencephalon develops from the rhombencephalon and gives rise to two structures: the pons and the cerebellum.^[2] The alar plate produces sensory neuroblasts, which will give rise to the solitary nucleus and its special visceral afferent (SVA) column; the cochlear and vestibular nuclei, which form the special somatic afferent (SSA) fibers of the vestibulocochlear nerve, the spinal and principal trigeminal nerve nuclei, which form the general somatic afferent column (GSA) of the trigeminal nerve, and the pontine nuclei which relays to the cerebellum.

Basal plate neuroblasts give rise to the abducens nucleus, which forms the general somatic efferent fibers (GSE); the facial and motor trigeminal nuclei, which form the special visceral efferent (SVE) column, and the superior salivatory nucleus, which forms the general visceral efferent fibers (GVE) of the facial nerve.

Nuclei

A number of cranial nerve nuclei are present in the pons:

• mid-pons: the  principal sensory nucleus of the trigeminal nerve (V)
• mid-pons: the motor nucleus for the trigeminal nerve (V)
• lower down in the pons: abducens nucleus (VI)
• lower down in the pons: facial nerve nucleus (VII)
• lower down in the pons: vestibulocochlear nuclei (vestibular nuclei and cochlear nuclei) (VIII)

Function

Functions of these four cranial nerves (V-VIII) include regulation of respiration, control of involuntary actions, sensory roles in hearing, equilibrium, and taste, and in facial sensations such as touch and pain, as well as motor roles in eye movement, facial expressions, chewing, swallowing, and the secretion of saliva and tears.^[2]

The pons contains nuclei that relay signals from the forebrain to the cerebellum, along with nuclei that deal primarily with sleep, respiration, swallowing, bladder control, hearing, equilibrium, taste, eye movement, facial expressions, facial sensation, and posture.^[2]

Within the pons is the pneumotaxic center consisting of the subparabrachial and the medial parabrachial nuclei. This center regulates the change from inhalation to exhalation.^[2]

The pons is implicated in sleep paralysis, and may also play a role in generating dreams.^[9]

Clinical significance

• Central pontine myelinolysis is a demyelinating disease that causes difficulty with sense of balance, walking, sense of touch, swallowing and speaking. In a clinical setting, it is often associated with transplant or rapid correction of blood sodium. Undiagnosed, it can lead to death or locked-in syndrome.

Other animals

Evolution

The pons first evolved as an offshoot of the medullary reticular formation.^[10] Since lampreys possess a pons, it has been argued that it must have evolved as a region distinct from the medulla by the time the first agnathans appeared, 525 million years ago.^[11]

Additional images

• 
  Location and topography of pons (animation)
• 
  Axial section of the pons, at its upper part
• 
  Hind- and mid-brains; posterolateral view
• 
  Median sagittal section of brain
• 
  Nuclei of the pons and brainstem
• 
  Cerebrum. Deep dissection. Inferior dissection.

References

• Pritchard, TE & Alloway, D (1999). Medical neuroscience. Hayes Barton Press. ISBN 978-1-59377-200-0.
• Butler, AB & Hodos, W (2005). Comparative vertebrate neuroanatomy: evolution and adaptation. Wiley-Blackwell. ISBN 978-0-471-21005-4.

External links

Wikimedia Commons has media related to Pons.

• Diagram at UCC
• Stained brain slice images which include the "Pons" at the BrainMaps project

This page was last edited on 24 May 2024, at 20:52