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Pelubiprofen

From Wikipedia, the free encyclopedia

Pelubiprofen
Clinical data
Trade namesPelubi
Legal status
Legal status
  • Rx in several countries
Identifiers
  • 2-[4-[(E)-(2-Oxocyclohexylidene)methyl]phenyl]propanoic acid
CAS Number
PubChem CID
DrugBank
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC16H18O3
Molar mass258.317 g·mol−1
3D model (JSmol)
  • CC(C1=CC=C(C=C1)/C=C/2\CCCCC2=O)C(=O)O
  • InChI=1S/C16H18O3/c1-11(16(18)19)13-8-6-12(7-9-13)10-14-4-2-3-5-15(14)17/h6-11H,2-5H2,1H3,(H,18,19)/b14-10+
  • Key:AUZUGWXLBGZUPP-GXDHUFHOSA-N

Pelubiprofen is a nonsteroidal anti-inflammatory drug of the profen class used to treat back pain and osteoarthritis.[1]

Pelubiprofen was developed in South Korea by Daewon Pharmaceuticals and it is marketed in Korea and Russia,[2] among other countries.

Research

Pelubiprofen is being studied for use in combination with eperisone.[3]

Because pelubiprofen has low water solubility, development of salt formulations with better solubility are being studied.[4]

References

  1. ^ "Pelubiprofen - Daewon Pharmaceutical". AdisInsight. Springer Nature Switzerland AG.
  2. ^ Chan-Hyuk K (26 September 2023). "Daewon Pharm wins $3 million deal to export Pelubi to Indonesia". Korea Biomedial Review.
  3. ^ "(Eperisone + pelubiprofen) by Daewon Pharmaceutical for Low Back Pain: Likelihood of Approval". pharmaceutical-technology.com. 5 June 2023.
  4. ^ Park JY, Oh DH, Park SW, Chae BR, Kim CW, Han SH, et al. (May 2021). "Development of Pelubiprofen Tromethamine with Improved Gastrointestinal Safety and Absorption". Pharmaceutics. 13 (5): 745. doi:10.3390/pharmaceutics13050745. PMC 8158122. PMID 34070062.
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This page was last edited on 23 May 2024, at 09:55
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