This is a list of investigational sexual dysfunction drugs, or drugs that are currently under development for clinical treatment of sexual dysfunction but are not yet approved. Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses.
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Atrophic vaginitis
- Estetrol (E4; Donesta) – estrogen receptor agonist (Estetrol - Mithra Pharmaceuticals - AdisInsight)
- Lasofoxifene (CP-336156, CP-336156-CB, Fablyn, Oporia) – selective estrogen receptor modulator (Lasofoxifene - Sermonix Pharmaceuticals - AdisInsight)
Erectile dysfunction
- HCP-1302 – undefined mechanism of action (HCP 1302 - AdisInsight)
- Nitroglycerin gel (Eroxon, Futura, MED-2001–MED-2005) – nitric oxide donor (Nitroglycerin gel - Futura Medical - AdisInsight)
- Tadalafil/tamsulosin (HCP-1303, CKD-397, YBH-1603) (Tadalafil/tamsulosin - Hanmi Pharmaceutical - AdisInsight, Tadalafil/tamsulosin - Ildong Pharmaceutical - AdisInsight, Tadalafil/tamsulosin - Chong Kun Dang - AdisInsight, Tadalafil/tamsulosin - Yungjin Pharmaceutical - AdisInsight)
- TT-701 (LY-2452473) – selective androgen receptor modulator (OPK 88004 - AdisInsight)
Female anorgasmia
- Testosterone low-dose intranasal (MPP-14, TBS-2, Noseafix, Tefina) – androgen receptor agonist (Testosterone intranasal (low-dose) - Acerus Pharmaceuticals - AdisInsight)
Female sexual dysfunction
- BP-101 – undefined mechanism of action (BP 101 - Ovoca Bio - AdisInsight)
- Bupropion/trazodone (S1P-104, S1P-205, Lorexys, Orexa) – norepinephrine reuptake inhibitor, nicotinic acetylcholine receptor antagonist, 5-HT2A receptor antagonist, α1-adrenergic receptor antagonist, weak serotonin reuptake inhibitor (Bupropion/trazodone - AdisInsight)
- Buspirone/testosterone (Lybridos) – 5-HT1A receptor partial agonist and androgen receptor agonist (Buspirone/testosterone - Emotional Brain - AdisInsight)
- Lasofoxifene (CP-336156, CP-336156-CB, Fablyn, Oporia) – selective estrogen receptor modulator (Lasofoxifene - Sermonix Pharmaceuticals - AdisInsight)
- PL-6983 – selective MC4 receptor agonist (Research programme: sexual dysfunction therapy - Palatin Technologies - AdisInsight)
- Sildenafil/testosterone (Lybrido) – PDE5 inhibitor and androgen receptor agonist (Sildenafil/testosterone - Emotional Brain - AdisInsight)
- TGFK09SD – 5-HT1A receptor agonist (TGFK 09SD - AdisInsight)
Premature ejaculation
- Clomipramine/sildenafil (CDFR-0812) – serotonin reuptake inhibitor and PDE5 inhibitor (Clomipramine/sildenafil - CTC Bio - AdisInsight)
- DA-8031 – serotonin reuptake inhibitor (DA 8031 - AdisInsight)
- IX-01 – oxytocin receptor antagonist (Cligosiban - Ixchelsis - AdisInsight)
- OnabotulinumtoxinA (botulinum toxin A, Botox) – acetylcholine release inhibitor (Onabotulinum toxin A - AbbVie - AdisInsight)
Unspecified
- Vilazodone (Viibryd, EMD-68843, SB-659746A) – 5-HT1A receptor partial agonist and serotonin reuptake inhibitor (Vilazodone - AbbVie - AdisInsight)
See also
References
External links
This page was last edited on 10 December 2023, at 23:42