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From Wikipedia, the free encyclopedia

HPSE2
Identifiers
AliasesHPSE2, HPA2, HPR2, UFS, UFS1, heparanase 2 (inactive)
External IDsOMIM: 613469 MGI: 2685814 HomoloGene: 19680 GeneCards: HPSE2
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001166244
NM_001166245
NM_001166246
NM_021828

NM_001081257

RefSeq (protein)

NP_001159716
NP_001159717
NP_001159718
NP_068600

NP_001074726

Location (UCSC)Chr 10: 98.46 – 99.24 MbChr 19: 42.77 – 43.38 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Heparanase-2 is an enzyme that in humans is encoded by the HPSE2 gene.[5][6]


It may be associated with urofacial syndrome.[7]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000172987 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000074852 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ McKenzie E, Tyson K, Stamps A, Smith P, Turner P, Barry R, Hircock M, Patel S, Barry E, Stubberfield C, Terrett J, Page M (Oct 2000). "Cloning and expression profiling of Hpa2, a novel mammalian heparanase family member". Biochem Biophys Res Commun. 276 (3): 1170–7. doi:10.1006/bbrc.2000.3586. PMID 11027606.
  6. ^ "Entrez Gene: HPSE2 heparanase 2".
  7. ^ Daly SB, Urquhart JE, Hilton E, et al. (June 2010). "Mutations in HPSE2 Cause Urofacial Syndrome". Am J Hum Genet. 86 (6): 963–969. doi:10.1016/j.ajhg.2010.05.006. PMC 3032078. PMID 20560210.

Further reading


This page was last edited on 16 January 2024, at 11:00
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