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Dipeptidase 2

From Wikipedia, the free encyclopedia

DPEP2
Identifiers
AliasesDPEP2, MBD2, dipeptidase 2
External IDsOMIM: 609925 MGI: 2442042 HomoloGene: 49703 GeneCards: DPEP2
Orthologs
SpeciesHumanMouse
Entrez

64174

319446

Ensembl

ENSG00000167261

ENSMUSG00000053687

UniProt

Q9H4A9

Q8C255

RefSeq (mRNA)

NM_022355
NM_001324159
NM_001369657

NM_001301204
NM_001301205
NM_176913

RefSeq (protein)

NP_001311088
NP_071750
NP_001356586

NP_001288133
NP_001288134
NP_795887

Location (UCSC)Chr 16: 67.99 – 68 Mbn/a
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Dipeptidase 2 (DPEP2) is a protein which in humans is encoded by the DPEP2 gene.[4]

DPEP2 belongs to the membrane-bound dipeptidase (EC 3.4.13.19) family. These enzymes hydrolyze a variety of dipeptides, including leukotriene D4, the beta-lactam ring of some antibiotics, and cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000167261 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ Habib GM, Shi ZZ, Cuevas AA, Lieberman MW (July 2003). "Identification of two additional members of the membrane-bound dipeptidase family". The FASEB Journal. 17 (10): 1313–5. doi:10.1096/fj.02-0899fje. PMID 12738806. S2CID 15252871.
  5. ^ "Entrez Gene: Dipeptidase 2".

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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This page was last edited on 28 March 2024, at 06:27
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