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Peruvósido

De Wikipedia, la enciclopedia libre

 
Peruvósido
Nombre IUPAC
(3β,5β,8ξ,9ξ)- 3-[(6-deoxy- 3-O-methyl- α-D- glycero- hexopyranosyl)oxy]- 14-hydroxy- 19-oxocard- 20(22)enolide
General
Otros nombres (3S,5R,10R,13R,14S,17R)- 3-[(2S,5R)- 3,5-dihydroxy- 4-methoxy- 6-methyloxan- 2-yl]oxy- 14-hydroxy- 13-methyl- 17-(5-oxo-2H-furan-3-yl)- 1,2,3,4,5,6,7,8,9,11,12,15,16,17- tetradecahydrocyclopenta[a]phenanthrene- 10-carbaldehyde
Fórmula estructural
Imagen de la estructura
Fórmula molecular C30H44O9 
Identificadores
Número CAS 1182-87-2[1]​
ChEBI 135825
ChEMBL 1075790
ChemSpider 16498835
DrugBank 13756
PubChem 14449
UNII CT36KGC6A6
O=C\1OC/C(=C/1)[C@H]6CC[C@@]5(O)[C@]6(C)CC[C@H]3[C@H]5CC[C@@H]4C[C@@H](O[C@@H]2O[C@@H](C)[C@H](O)[C@@H](OC)[C@@H]2O)CC[C@]34C=O
InChI=1S/C30H44O9/c1-16-24(33)26(36-3)25(34)27(38-16)39-19-6-10-29(15-31)18(13-19)4-5-22-21(29)7-9-28(2)20(8-11-30(22,28)35)17-12-23(32)37-14-17/h12,15-16,18-22,24-27,33-35H,4-11,13-14H2,1-3H3/t16-,18+,19-,20+,21-,22+,24-,25-,26+,27-,28+,29+,30-/m0/s1
Key: PMTSPAGBAFCORP-HBUONDEYSA-N
Propiedades físicas
Masa molar 548,665 g/mol
Valores en el SI y en condiciones estándar
(25 ℃ y 1 atm), salvo que se indique lo contrario.
[editar datos en Wikidata]

El peruvósido (o canogenina tevetósido) es un glucósido cardíaco[2]​ para la insuficiencia cardiaca.[3]​

Se extrae de la planta Thevetia neriifolia.[3]​

Referencias

  1. ↑ Número CAS
  2. ↑ Arora, R. B.; Rangaswami, S. (1972). Peruvoside and Other Cardiotonic Glycoside[s] of Thevetia neriifolia Juss: Chemical, Pharmacological, and Clinical Studies. New Delhi, India: Thomson. LCCN 78900408. 
  3. ↑ a b Bhatia, M. L.; Manchanda, S. C.; Roy, S. B. (1970). «Haemodynamic Studies with Peruvoside in Human Congestive Heart Failure». British Medical Journal 3 (5725): 740-743. PMC 1701679. PMID 4919553. doi:10.1136/bmj.3.5725.740. 

Enlaces externos

Esta página se editó por última vez el 10 oct 2019 a las 07:08.
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