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Interleucina 7

De Wikipedia, la enciclopedia libre

interleukin 7
Estructuras disponibles
PDB

Buscar ortólogos: PDBe, RCSB

 Lista de códigos PDB
3DI2 , 3DI3
Identificadores
Símbolo IL7 (HGNC: 6023)
Identificadores
externos
Locus Cr. 8 q12-q13
Patrón de expresión de ARNm
ancho=250px
Más información
Ortólogos
Especies
Humano Ratón
Entrez
3574 16196
Ensembl
Véase HS Véase MM
UniProt
P13232  P10168 
RefSeq
(ARNm)
NM_000880 NM_008371
RefSeq
(proteína) NCBI
NP_000871 NP_032397
Ubicación (UCSC)
Cr. 8:
79.59 – 79.72 Mb
PubMed (Búsqueda)
[1]


[2]
[editar datos en Wikidata]

La interleucina 7 es una citoquina de 27 kDa producida por las células del estroma de la médula ósea y por los fibroblastos. Actúa sobre los progenitores linfoide inmaduros, induciendo su desarrollo.[1]​[2]​[3]​[4]​[5]​

Referencias

  1. ↑ Namen AE, Lupton S, Hjerrild K, Wignall J, Mochizuki DY, Schmierer A, Mosley B, March CJ, Urdal D, Gillis S (1988). «Stimulation of B-cell progenitors by cloned murine interleukin-7». Nature 333 (6173): 571-3. Bibcode:1988Natur.333..571N. PMID 3259677. doi:10.1038/333571a0. 
  2. ↑ Goodwin RG, Lupton S, Schmierer A, Hjerrild KJ, Jerzy R, Clevenger W, Gillis S, Cosman D, Namen AE (1989). «Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells». Proc. Natl. Acad. Sci. U.S.A. 86 (1): 302-6. Bibcode:1989PNAS...86..302G. PMC 286452. PMID 2643102. doi:10.1073/pnas.86.1.302. 
  3. ↑ Sutherland GR, Baker E, Fernandez KE, Callen DF, Goodwin RG, Lupton S, Namen AE, Shannon MF, Vadas MA (1989). «The gene for human interleukin 7 (IL7) is at 8q12-13». Hum. Genet. 82 (4): 371-2. PMID 2786840. doi:10.1007/BF00274000. 
  4. ↑ Lupton SD, Gimpel S, Jerzy R, et al. (1990). «Characterization of the human and murine IL-7 genes». J. Immunol. 144 (9): 3592-601. PMID 2329282. 
  5. ↑ Alves, BIREME / OPAS / OMS-Márcio. «DeCS». Consultado el 18 de mayo de 2023. 
Esta página se editó por última vez el 18 may 2023 a las 10:06.
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