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Amidofosforribosiltransferasa

De Wikipedia, la enciclopedia libre

Amidofosforribosiltransferasa
Estructuras disponibles
PDB

Buscar ortólogos: PDBe, RCSB

 Estructuras enzimáticas
RCSB PDB, PDBe, PDBsum
Identificadores
Símbolo PPAT (HGNC: 9238)
Identificadores
externos
 Bases de datos de enzimas
IntEnz: entrada en IntEnz
BRENDA: entrada en BRENDA
ExPASy: NiceZime view
KEGG: entrada en KEEG
PRIAM: perfil PRIAM
ExplorEnz: entrada en ExplorEnz
MetaCyc: vía metabólica
Número EC 2.4.2.14
Locus Cr. 4 pterq21
Ortólogos
Especies
Humano Ratón
Entrez
5471
UniProt
Q06203   n/a
RefSeq
(ARNm)
NM_002703 n/a
PubMed (Búsqueda)
[1]


PMC (Búsqueda)
[2]
[editar datos en Wikidata]


La amidofosforribosiltransferasa (o fosforribosil pirofosfato amidotransferasa) es una enzima que cataliza la conversión de fosforribosil pirofosfato (PRPP) en 5-fosforribosilamina (5PRA), mediante la escisión del grupo amino de la cadena lateral de la glutamina y su posterior transferencia al PRPP. Esta reacción es crucial en la síntesis de purinas. El gen que codifica esta enzima se localiza en el cromosoma 4, en la posición pterq21.

Enlaces externos

Esta página se editó por última vez el 22 oct 2019 a las 22:56.
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