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ARAF
Estructuras disponibles
PDB

Buscar ortólogos: PDBe, RCSB

 Estructuras enzimáticas
Identificadores
Nomenclatura
 Otros nombres
Proto-oncogén A-Raf
Símbolo ARAF (HGNC: 646)
Identificadores
externos
Número EC 2.7.11.1
Locus Cr. X p11.3-p11.23
Estructura/Función proteica
Tamaño 606 (aminoácidos)
Ortólogos
Especies
Humano Ratón
Entrez
369
UniProt
P10398   n/a
RefSeq
(ARNm)
NM_001654 n/a
PubMed (Búsqueda)
[1]


PMC (Búsqueda)
[2]

La serina/treonina cinasa protooncogénica A-Raf (ARAF) es una enzima codificada en humanos por el gen HGNC ARAF .[1]​ Es una enzima cinasa perteneciente a la familia las serina/treonina proteína cinasas no específicas (EC 2.7.11.1).

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Transcription

Interacciones

La proteína ARAF ha demostrado ser capaz de interaccionar con:

Referencias

  1. «Entrez Gene: ARAF V-raf murine sarcoma 3611 viral oncogene homolog». 
  2. a b c d e Yuryev, Anton; Wennogle Lawrence P (Feb. de 2003). «Novel raf kinase protein-protein interactions found by an exhaustive yeast two-hybrid analysis». Genomics (United States) 81 (2): 112-25. ISSN 0888-7543. PMID 12620389. 
  3. a b c Yuryev, A; Ono M, Goff S A, Macaluso F, Wennogle L P (Jul. de 2000). «Isoform-specific localization of A-RAF in mitochondria». Mol. Cell. Biol. (UNITED STATES) 20 (13): 4870-8. ISSN 0270-7306. PMID 10848612. 
  4. Yin, Xiang L; Chen She, Gu Jian X (Feb. de 2002). «Identification of TH1 as an interaction partner of A-Raf kinase». Mol. Cell. Biochem. (Netherlands) 231 (1-2): 69-74. ISSN 0300-8177. PMID 11952167. 
  5. Yin, Xiang L; Chen She, Yan Jun, Hu Yun, Gu Jian X (Feb. de 2002). «Identification of interaction between MEK2 and A-Raf-1». Biochim. Biophys. Acta (Netherlands) 1589 (1): 71-6. ISSN 0006-3002. PMID 11909642. 
Esta página se editó por última vez el 2 dic 2021 a las 21:59.
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