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William DeVries

From Wikipedia, the free encyclopedia

William DeVries
DeVries in 2002
Born
William Castle DeVries

(1943-12-19) December 19, 1943 (age 80)
NationalityAmerican
Known forDr. William DeVries and his surgical team replaced a diseased heart with the Jarvik-7, the first permanent artificial heart ever used for a human patient.
Scientific career
Fieldscardiothoracic
surgeon

William Castle DeVries (born December 19, 1943) is an American cardiothoracic surgeon, mainly known for the first transplant of a TAH (total artificial heart) using the Jarvik-7 model.

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  • Anita Silvey: 2010 National Book Festival

Transcription

>> From the Library of Congress in Washington, D.C. >> And now I am very pleased to introduce the next author. You've seen lots of good authors today. Well, Anita Silvey knows all about good children's books. She served as the publisher of children's books for Houghton Mifflin and as the editor of The Horn Book, which is the magazine about children's literature. Her books include 100 Best Books for Children and 500 Great Books for Teens. Her latest book is Everything I Needed To Know I Learned From A Children's Book, which seems pretty true. And she's currently working on the Children's Book-A-Day Almanac as well as an illustrated biography for children called Henry Knox: Bookseller, Soldier, Patriot. She has said only the very best of anything can be good enough for the young. Lucky for the young Anita Silvey is one of the best. Please join me in welcoming Anita Silvey. [ Applause ] >> Anita Silvey: Thank you. Do I have any book lovers out here? Do I have any book lovers? This is for book lovers. You know we talk about [inaudible], vivre, V-I-V-R-E, it's [inaudible] at this event, okay. It's joy of books, and I must admit as I was, I was in a little go cart and, you know, I was coming from the Capitol going to the Monument, and I sort of had a heat hallucination, and I was thinking about how I got here. And I am somebody who had a lot of detours on my way to being an author and for those in the audience, you know, if you think you're in detour, I can only tell you my story. In 1970, I arrived in Boston and I wanted to teach and I couldn't find, no one would hire me, and at that point in time there was an opening in the children's book department at Little Brown and Company, and I said, oh, gee, if I can't teach kids, wouldn't it be fun to work on books for them? It was sort of like in Citizen Kane he says, "Oh, I think it will be fun to run a newspaper," you know, it just and with that spirit I walked into the children's book department and I fell in love right away because I was making books, I was creating books. I spent the next 32 years helping other people make books and my dream was that someday I could make my own. And in 1995, I finished my first reference book for children. It was called Children's Books and Their Creators. I was published at Houghton Mifflin when it came out, and I remember the day that it arrived and by the way I started big and have gotten smaller, and I recommend that, too, okay, you know, do your ambitious project first and then get smaller. It was 800 pages, you know, it's a great door stop. It really is. I used to say it was the cheapest in the industry for its weight. It weighed around three pounds, and when I saw that book and I held it in my hands that night, I just broke down sobbing and I said this is what I've always wanted to do and I've got to find a way to do it. So, I saved a lot of money and in 2001 I took that vow of authorship; perseverance, determination, poverty. [Laughter] That is the author's vow. You have to be willing to go the distance, not to worry about money if you want to do what you want to do. And so I have now had about 10 years of writing books both for children and writing what I love to do is I love to write about children's books. Five years ago one of my best friends in publishing called me up. It was a cold winter's day. It was so far from this that it amazes me to think about it, and she said I'm going to run a title by you and I'm going to run a concept, and she said the title is Everything I Needed to Know I Learned From A Children's Book and the concept is that you're going to interview 100 some people none of whom you know or who necessarily want to talk to you about the children's book that influenced their lives and we're going to choose these from among the leaders in society. I believe that it took me a fraction of a second to say, you've got me, I'm on board. I would love to do this. Because everywhere I go and every place I talk to people one of the things I always ask people is what did you read as a child and what do you remember about it and who gave it to you? And so I began, I want to say it was easily the happiest two years of my creative life setting up interviews with people, my editor and I came up with a list. We came up with a list of the 500 people in the United States that if we could get interviews with them that's who we'd want, and I began person after person after person to try to talk to them and to try to hear what children's book had affected their lives. It was an amazing experience, you know, I'd wake up in the morning and the first thing I'd think of is, is this the day I talk to Julianne Moore? Is it Kirk Douglas today? Who's on docket today? And I began to have this series of interviews with people that changed me and changed the way I look at books because I always would have told you that I think books have profound influence, but I never realized what that influence was. I never had the evidence. One of the things that people often ask me is they often say what was your biggest surprise in the interviews? And I have to say I was talking to Kirk Douglas by the way had just turned 90, and I had been led to believe that he loved Mike Mulligan and His Steam Shovel. And so I was preparing for Mike Mulligan and his Steam Shovel interview, and he picked up the phone and I gave him the title of the book and he said, oh, that's easy. He said the book I want to talk to you about is The Bobbsey Twins. I said, oh, you've got to be kidding. I think I laughed, you know, because I was so unprepared for that and I said, well, why the Bobbsey Twins? And then he told me and it made perfect sense. He said my family was an immigrant family, my parents did not read English, my sister was the first person to read -- his sister, Betty -- and he said that was her favorite book and when I was a little boy she sat me on the couch and she read me the Bobbsey Twins. And he said because of the Bobbsey Twins I learned to read and if had not learned to read, I would have had no career as an actor. And those were the kinds of testimonies again and again and again, you know, it's not only people who love books who are affected by them; it's everyone who reads a children's book. The dancer, Edward Villella, said I only think I read one book as a child, but I remember it as it if were yesterday and the book that affected him not surprisingly is the Little Engine That Could. He was a man, a testimony to overcoming things as was by the way the sportscaster Tiki Barber that was his favorite book as a child. I was shocked to find out how many people chose careers based on children's books. I would not have thought that. I would not have thought that you pick up a book, you read it, and you know what you want to do for your life's work and yet again and again people gave me that testimony. David McCullough, the historian, said that when he was age 9 he met his first alternate historian in a book by Robert Lawson called Ben and Me, and he said I knew from that book on that I wanted to write history in just as exciting way as Robert Lawson could write it. Robert Kennedy, Jr., picked up a book when he was around 9 or 10, and it was Jean Craighead George's My Side of The Mountain. He was so taken with this book and for those who know the book by the way there's a young boy in there who becomes a falconer and so Robert wrote to the author, Jean Craighead George, and basically the letter read something like I want to get a falcon. Can you give me any lines that I can use on my mother, Ethel, to get her to give me one? [Laughter] Okay, so he wrote to his favorite author. Evidently Jean gave him the justification that his mother needed and he got a falcon, and he said that working with a falcon led him to a career in environmental law and in pursuing preserving the wilderness, and he said when I went to school all of the kids in my class all admitted that the book that had had the most profound effect on us was My Side of the Mountain and by the way the beauty of that, by the way Jean Craighead George just turned 90 this year, and the beauty of that is that later on in their lives they came together and he was able to tell her that story and so I was able to record it for the book, which is a wonderful thing to have. Robert Ballard, who raised the Titanic, anyone want to guess what his favorite book was? >> 10,000 Leagues. >> Anita Silvey: Absolutely. 10,000 Leagues Under The Sea. He said I'm a modern-day Captain Nemo. He went to his parents and he said how do I get to do this? And they said you need to pursue a degree in oceanography and he said so I went and I got a degree and then I asked them how do I do other things? And they told me other things to do. As he says in his essay, all children have dreams and what we need are adults to tell us that we can live these dreams, that we can have these dreams. I wasn't surprised, I've always aside that children read for two things; they read for character and they read for plot. And so there were a lot of people who talked to me about their favorite character out of children's books. For Judy Bloom, for writer Judy Bloom, that character was Madeline, and she so loved the Madeline books that she hid the one from the library under her pillow so her mother would not return it and so if you were Judy Bloom's librarian, she's sorry, but she never did bring it back. It was, she said I now know my mother might have bought it for me, but I loved that book too much to give it up. There is one character out of fiction that has probably influenced more people than any other; Simone de Beauvoir, Julianne Moore, Hilary Clinton, Judy Woodruff, Bobbie Ann Mason and that is from Little Women, Jo March, has had a profound effect on generations of women. And one of my favorite stories came from country western singer heartthrob Brad Paisley, who had a baby about two years ago, and he and his wife were in disagreement about how to name the baby because Brad Paisley wanted to name the baby after his favorite character in children's books, and his wife clearly didn't want to, okay, so they argue throughout the hospital stay and eventually on the way home they have to make a decision and so Brad Paisley said I got the certificate and I wrote on it the name of my son and he said I kept the pen because I wanted to give that pen someday to my son and say with this pen my favorite author wrote a book and with this pen we gave you a name based on that book so that you can have it and hence we have in this world William Huckleberry Paisley. So, Huck Finn is alive and well in the Paisley family. Some of the interviews were absolutely spectacular. I think my, I had two favorites I must admit. I'm in love with Pete Seeger. I just admit it outright, you know, I don't hide it at all, and I spent two hours on the phone with him and he sang to me while I was on the phone. He sang me his favorite songs from childhood. I couldn't record that, but it was a wonderful interview, but I had one of the last interviews with the painter N.C. Wyeth, and he had, painter Andrew Wyeth, the son of N.C. Wyeth, and his staff had been protecting him, and I didn't realize that he was sick but when we got on the phone that day, he started to talk about his father's legacy to him. He said when he was a little boy his father put him on his lap and he read Treasure Island to him and he showed him the images that he was creating. Wyeth said the day that I saw the image of blind [inaudible] groping down the row in Treasure Island he said that was the day that I knew I wanted to become an artist. He said my father passed on the idea of creating art to me. Other times it's a single line in a book that people remember. Jay Leno's favorite book was Mike Mulligan and His Steam Shovel, and the line that he loved from it was the line where it says, "the harder Maryanne dug, the more people who came the harder and faster Maryanne dug." And Jay Leno said I was always a show off and I realized that that the more of a crowd I had the more of a show off I was. William DeVries here of Walter Reed, by the way in this city, is the first doctor to insert the artificial heart, and his line that he had remembered, he said I have remembered it every professional day of my life as a doctor and it was a line from the book his mother gave him, it was Wizard of Oz, and his line where the tins woodsman said, " I would bear all the unhappiness in the world if only I had a heart," and he said I have carried that line with me through everything that I've done. The testimonies were testimonies about family, about sharing books with children that had been shared with them. Scott Simon of NPR talked about his new Chinese daughters that he had, you know, they had adopted and when he's away from them he reads Goodnight Moon on the telephone to them at night, and he said we always fall asleep under the same moon. And Linda Johnson Robb, L.B.J.'s daughter, gave one of the loveliest testimonies. Her mother and a woman named Sel [phonetic] Marshall were college roommates and as Linda said Sel's little boy, Jimmy, went on to create children's books. That is, of course, James Marshall, and he did the classic Miss Nelson is Missing, and so Linda said we got those books as a child, we shared them with our children, and she said they're on my shelf right now for when we have grandchildren and we will pass them on. And she said that books tie the generations of my family together. When I touch this book, I'm with my mother, I'm with my own children, I'm in my own childhood, and now someday I will pass that on and that is really what great children's books do, but I have to say that the thing that was remarkable of every one of these interviews people would say to me you'll remember the name of the author, I've forgotten it, but I remember the name of the person who gave it to me. They're very important people. They remember the name of their second grade teacher, the public librarian or the school librarian that handed them the book, the parent, anyone who gave them those books they, all of these memories were not just a memory of a book they were memory of the book and the person who had brought them together. And as they talked about this, I have to say that their voices got softer. My first interview was with Steve Forbes. I was terrified of him. He's been known to eat the press for lunch, and when I said to him did you like reading as a child he said I hated to read as a child, and I thought, oh, dear, this isn't off on a very good foot and what are we going to do? And then he said but you know I loved being read to and my mother would take me in her lap and she would share books with me and suddenly his voice got very soft and he became a young boy again and it was a totally different interview as he talked about what his mother had done for him sharing books with him. So for those of you who are passing on books to children you are becoming part of their best memories, you are becoming part of what makes them a human being, and you are giving them something very precious and something very vital to remember, but it will take the children in your life a long time before they'll tell you this and they maybe can't tell you this, but I'm really here today because what I hope is that all of you will find that this glorious festival some great children's books to pass on to your children and someday hopefully if I live long enough and I don't stay in too many heat waves like this one, I have a better chance of it. When I'm interviewing them, they will be able to tell me about a book that you put in their hands of something you gave them, of something you passed on to them because you remembered to make sure to get the right book for the right child at the right time and that is what my book is all about. Thank you so much, and I'd love to hear from all of you. [ Applause ] This is your chance to ask questions, to tell me your, and somebody is going to I hope tell me your favorite books and whatever you want to know. All right. >> I was wondering what children's book or line was it for you that really inspired you? >> Anita Silvey: What book was it for me? I have to say, you know, tell me, give me an age and I have a different book, but I will tell you the one that's the most important to me over time and it sits right next to my desk and it was purchased by my mother's great aunt. She was born in 1865 at the end of the Civil War. She read it, she inscribed it to my mother, my mother passed it on to me and every time I touch that book everybody I, all the women in my family are there and that's Frances Hodgson's Burnett The Secret Garden and that is still to this day I must admit it's my favorite book. What's your favorite book? That's what I want to know. >> Uhm, I have a lot. I probably can't decide. >> Anita Silvey: Okay. All right. [Laughter] All right. Thank you, yes? >> I'm with you on The Secret Garden. That and Anne of Green Gables is my favorite. >> Anita Silvey: Yeah. >> But I'm sort of an aspiring children's book author and the book I've been working on for some time doesn't really fit a category, and I keep hearing things like unless you show a character growth, unless you do this or do that your book won't be published, and I guess I'm looking for some kind of comfort that as long as the book is good enough that it will have a shot at being published. >> Anita Silvey: Yeah, you're going to hear that from me because one of the things that you find, you know, this is the sense of writers. There are a lot of rules for writers, and if you go to conferences, go to conferences because you can learn things, they'll give you all those rules for writers and the only thing that's true of rules for writers is they're meant to be broken. Almost every single classic that we have for children breaks the standard convention of the day, but what the author had to have was a willingness to persevere. So, we know, for instance, Dr. Seuss is our most rejected classic writer. He was rejected somewhere around the range of 25 to 27 times and people didn't like him because they didn't like rhymed verse and nobody published rhymed verse at that time, and he didn't have any morals or messages and everybody was publishing very message-laden books. One day after his 27th rejection he was walking down the street and he ran into an old Dartmouth classmate, and he was singing his tale of woe and that classmate said to him this is really quite wonderful, you know, they've just made me the children's book editor at Van Guard and I'm going to publish your book and Seuss said, yes, but I've just told you every one has rejected it; don't you want to read it? And his friend said I wouldn't know a children's book if it bit me by the ankles. [Laughter] But I need one and you have one so we are on board, and he gave him a contract that day. Okay, so, persevere, what do you need to write, listen to people, listen to feedback, but write the book you need to write because that's the most important book. I absolutely encourage you with that. That's how we get great writers. Thank you. Thank you. Yes, over here? >> Yeah, my favorite book, E.B. White had the same problem. Charlotte's Web. >> Anita Silvey: Charlotte's Web. And how did you find it? >> My father bought it for me and it's the first book he ever bought for me so that's why I remember it. >> Anita Silvey: Okay. >> Anyways my question for you is, what's something to really remember and consider when recommending books to reluctant readers? >> Anita Silvey: Recommending books to reluctant readers, you know, first of all get help, you know, in your local library. They know what's working in that area, you know, we just have Jeff Smith here. One of the things I saw is graphic novels are books, you know, Diary of a Wimpy Kid, Jeff's books, these are making great strides with reluctant readers. So don't judge the kind of literature; just get them something that engages them and, you know, there are for each age group I think a good librarian or good bookseller could give you something that we know is working, but it's important to honor their taste; not to put our taste on top of it sometimes. Sometimes all they're reluctant to read is what we want them to read. They're not reluctant to read the books that they find exciting. I have parents say to me, oh, my kids only want to read information books. How do I stop them? And I say you don't stop them. You give them more information books to read. So, you know, it's, you know, people get going again. J.K. Rowling turned people back into readers; Jeff Kinney is turning people back into readers; Stephenie Meyer has turned teenagers back into readers; we've got a lot of great people going now so just don't give up with it. All right. And I have another question here. >> I personally like reading by myself best, but do you like someone reading to you or you reading by yourself? >> Anita Silvey: Oh, boy, if anybody reads to me, that's a real privilege, and you know, people as you get older they don't, but I love to listen to tapes where people read, but I like to, I just like to curl up with a book, you know, I always have. I did when I was your age and I do now. Either way it's great. If they read to you, it's great or, you know, if you read it, it's great. So just keep doing it. Just keep doing it. Thank you. All right, over here. >> Hi. I also have been writing for children and heard what you had said to the previous person here, but what about publishing on your own? I know more and more people are trying to do that. What advice can you give and then I'll tell you my book. >> Anita Silvey: Okay. One of the things that I, I teach publishing in the Simmons, I even have former students here. It's hard to believe they'd come to hear me again, but anyway one of the things I say to my students I believe that publishing on your own is becoming more and more legitimate. All that is needed is a review source that would actually review those books, and we would be in a whole other place with them. So, I know so many success stories of people who just didn't want to beat their heads against the brick wall anymore went and published their book on their own. There are some good places to do it through like iUniverse that help you with the process, and you know, if the book works, you can always sell those rights to publishers. So, it's not I'll publish on my own and I'll never be able to have another go at it. So, I think we're just at that time period where we're going to see more and more and more publish on their own and then publishers will pick up some of the more successful books. So, don't write it off as a possibility. >> Thank you, and my favorite book is very old, it's [inaudible]. Is Sally Goes to The Circus Alone. >> Anita Silvey: Oh, okay. >> It's very, very old, but a sneaky little girl who managed to go off on her own. >> Anita Silvey: And go to the circus, yeah. I'd love to go to the circus right now. An air conditioned circus. All right. Yes? Somebody over here. >> My question is, who was your mentor when you were in your childhood? >> Anita Silvey: I'm sorry? >> Who was your mentor? >> Anita Silvey: Oh, who was my mentor? In publishing, you know, I never, this is an honest story, I left publishing when I was 53 years old, and I never had a mentor. I had bosses, but they were sadistic. [Laughter] No, no, I mean they were my bosses, you know, they got a lot of work out of me, but they were never mentoring me. At age 54 I edited the book of Howe Miller, who was the former CEO of the company that I worked for, and I got my first mentor at the age of 54, and he is now by the way he's 87, and I tell him he's got to keep hanging in because I can bring to him all those questions as a writer that I need. So, as a writer, I've had a mentor but as somebody in publishing I never had one so, you know, it's never too late for a mentor, you know, it's also never too late for a happy childhood as we all know so thank you. That's a good question. Yes? >> I'm a school counselor and I'm always using books to, you know, encourage the children. I've read your book the 100 Best Books For Children, and I agree with a lot of them and there's one that wasn't in there. I was going to email but now I can tell you. I think it's the Five Chinese Brothers. >> Anita Silvey: Oh, yes, yes. >> I love that, and I was surprised it wasn't. >> Anita Silvey: Yeah, when you only have a, by the way 100 Best Books for Children was the most sadistic book that I ever did because I love to do 800 pages and 100 was just too short and so I had to leave out so many great things. I believe it's in the reading list, but I just had to leave out so many things. Thank you very much. Okay. One more question I think. >> Yes. I grew up reading Mary Poppins. >> Anita Silvey: Oh, a good one. >> All these stories from other countries. I am also a great aunt to boys growing up in sports-oriented homes as well as academic homes but sports so it is a challenge to not give them what I want but what they would enjoy. >> Anita Silvey: Yes, yeah. To remember the mantra is the right book for the right child at the right time and that is honoring the child. That is very important to do in all reading. We honor who they are as human beings. Okay. Thank you. One more question. I think we have one more. Quick one. >> Hi. I was wondering I have a question about what your advice would be for inspirational writers who would like to pursue writing as their job but considering how what the competition is for trying to publish a book. >> Anita Silvey: Yeah. One of the things that I say to all writers write what you have to write, look every now and then at what's published, but don't get consumed by it. Find your own voice, find what you have to say, keep going, perseverance is everything okay so just keep doing it and don't, there's that voice that's always going to say they don't need my book, they don't need me, I have nothing to say, I am insane, in fact, to be doing this in my pajamas at whatever hour, 3 in the morning, okay, that voice is always there. Don't give in to it, keep writing what you need to because you know what I finally realized is I could do books about what I loved, which was children's books that had never occurred to me so just keep going. That's always my advice. Keep going. Thank you all. Thank you very much. [ Applause ] >> This has been a presentation of the Library of Congress. Visit us at loc.gov.

Early years and medical school

William DeVries was born December 19, 1943, in Brooklyn Navy Yard. His father, Henry DeVries, was a Dutch immigrant who died in combat on the destroyer USS Kalk (DD-611) in 1944 during the Battle of Hollandia,[1] where he had enrolled as a naval surgeon. When his father died William was only six months old. He was raised by his grandmother and his mother who was a member of the Church of Jesus Christ of Latter-day Saints until he was five. After his mother remarried, the family was enlarged by eight more children and they all moved to Ogden, Utah, where he attended Ben Lomond High School and where he was an athlete being on the basketball and track teams.[2] During his childhood DeVries became an Eagle Scout.[3] Because the family was meeting financial difficulties, William had to work throughout his high school years to help out. He also won the Utah state finals in high jumping and thanks to his sport abilities he went to the University of Utah on a track scholarship. During college he was part of the Sigma Chi fraternity. He graduated in 1966 with a bachelor's degree in molecular and Genetic biology. Later on he went to medical school also at the University of Utah and received his M.D. degree in 1970.[4]

By the time he had finished with school, he had already built a family. He married his first wife, Ane Karen,[4] during the last year of college and had four children. During college he was able to hold down three or four jobs and yet he graduated top of his class and received the award for the most outstanding graduate.[5]

It was thanks to one of the jobs that he was involved in surgery. He assisted doctor Willem Johan Kolff during his work and during night he was paid to watch over the animals in the lab. In 1969 after some advice from doctor Keith Reemtsma, he decided to leave Salt Lake City and to start his residency in another hospital. That is also the year in which doctor Denton Cooley attempted his first artificial heart transplant in a patient, in Houston. Doctor Cooley's work would be an inspiration for doctor DeVries, who would later succeed in the transplant of the TAH. After he left Utah, he attended a series of job interviews. The first one was at the Massachusetts General Hospital in Boston. The day of the interview, on his way to the hospital, he witnessed a person being stabbed by another man, and helped the victim until he was carried to the emergency room. This episode was probably one of the reasons why he decided not to start his residency in Boston. The second interview he attended was at the Johns Hopkins hospital, but eventually he opted for a residency at the Duke University in North Carolina. At the end of his nine years surgical training, he headed back to Salt Lake City.[6]

The artificial heart

In 1979 Doctor DeVries went back to the University of Utah to become the chairman of thoracic and cardiovascular surgery; there, he used to perform two to five open-heart operations a week.[4] At that time the university was known for being one of the country's few pioneering centers for advanced surgery on vital organs and their transplanting and implanting into animals and humans.[4] In Salt Lake City he worked with doctor Robert Jarvik and doctor Kolff. By the time DeVries was back to Salt Lake City, the calves with artificial heart were able to live up to six, seven, even eight months. These results inspired him to take on with the work and so he started a series of long-term animal experiments. After two years of experiments, doctor DeVries and his colleagues tried to obtain the U.S. Food and Drug Administration (FDA) and the National Institutes of Health (NIH) approval. At the beginning, nobody really paid much consideration to the work, but after a while it started to acquire new attention, things changed, and even the NIH started to be interested in the project. Therefore, DeVries started to look for a suitable patient for the first attempt. In 1982, the FDA gave the approval to experiment the device on a human, and so a panel of six members at the University of Utah Medical Center started searching for a patient. The group was composed of two cardiologists, a psychiatrist, a nurse, a social worker and DeVries; the decision had to be unanimous.[7]

The first patient

The first patient was a Seattle dental surgeon named Barney Clark, affected with an end-stage congestive heart failure.[8] The seven-hour surgery was carried out on December 2, 1982, and it was successful. Doctor William DeVries, 38 years old at that time, was known to listen occasionally to rock music while performing surgery. In his first Jarvik-7 implant the operating room was hushed, except for the voice communications to the medical team and the quietly played strains of Joseph-Maurice Ravel's "Boléro".[4] The patient lived, but DeVries found much harder to manage the device on a patient rather than on a healthy animal. This carried to some complications which led part of the researchers to ask DeVries to turn off the device. In fact they did not want to lose the NIH approval and consequently their funds. DeVries refused to shut down the device, this caught the attention of the media, and made DeVries achieve the cover of Time magazine (December 10, 1984). Eventually, they had to deal with the issue of money. To keep Mr. Clark alive, he decided to sell the rights of his story to a newspaper for $1 million . Mr. Clark lived for 112 days after the surgery, as complications kept occurring and this led to multiorgan failure and eventually death.[9] Unfortunately Mr. Clark never recovered well enough to leave the hospital. In this period DeVries and his team had to face a series of issues due to the pressure of the media and the public. He was constantly obsessed with critics and legal issues concerning about what he was doing whether it was right or wrong. With the success of the first patient, DeVries wanted to go on with his trials, but there were not enough funds and medical insurance was never going to pay for such an experimental transplant. Consequently, DeVries found himself on a quest for fund raising, which, at the beginning did not succeed until Wendell Cherry, vice chairman of the Humana Inc. offered him to relocate in Louisville, Kentucky; in exchange Cherry offered to finance the next 100 implants.[10]

The Jarvik-7

The Jarvik-7 was a mechanical device, made of polyurethane[4] and aluminium,[11] which was used to replace the two ventricles of a human heart.

Jarvik-7 artificial heart

The pumping action came from air, compressed by an electrical unit located outside of the patient's body.[7] The human-made organ had two separate ventricles grafted with Dacron sleeves to the native atria and great vessels. It was powered by a 400-pound (180 kg[12]) air compressor, connected to the heart, through a tube coming out of the patient body. In order to give the patients the ability to move, it was also invented a portable power console which was the size of a briefcase. Since 1982, 350 patients have used the Jarvik-7 heart model, and its original design is still used for the modern Jarvik-7, although due to propriety passages the device name is now "SynCardia". In October 2004, the Jarvik-7 model was the first medical device to receive a full-FDA approval.[11]

In Louisville, Kentucky

After the offer from Wendell Cherry, DeVries decided to move to Louisville in order to continue with his work on the TAH although he knew that the reason why the Humana Inc. had given him such a generous offer was mainly due to the publicity that this project was to offer them. "Our name is now on every single newspaper in the world. This is the type of advertisement that you cannot buy. As far as I am concerned, you have made your money for the next hundred patients"[13] (Wendell Cherry). And even knowing this, DeVries accepted the deal because it was for medical advancement.

Bill Schroeder was his second candidate. The patient survived through the surgery, and initially did so well that when president Ronald Reagan phoned him, a week after the implant, he asked why his social security check was late. Unfortunately two weeks later mister Schroeder suffered of a series of infections and strokes that left him unable to speak. He lived for 620 days after the operation, during which he was able to leave the hospital and do a series of normal activities like traveling, attending a basketball game and even fishing.[11] Over the following years DeVries implanted a total of four artificial-hearts, and always had someone with a TAH in his facility.

Thanks to his work, the TAH was used in many hospitals, not as a permanent solution for diseased heart patient, but as a "bridge" in order to assist the heart and wait for a final transplant.[7]

In 1983, DeVries received the Golden Plate Award of the American Academy of Achievement.[14]

During 1987, 49 diseased hearts had been substituted by surgeons all over the world with a Jarvik-7 model.[7] In January 1988 DeVries was close to performing his fifth implantation, when a human donor heart was found for the patient. In January 1990 the approval was withdrawn, and the FDA ended the program. Before his retirement, in 1999, doctor DeVries decided, in 1988, to go back to traditional cardiovascular surgery. On December 29, 2000, he joined the United States Army Reserve as a lieutenant colonel, becoming at age 57 one of the oldest people to enter and complete the Officer Basic Course.[1] After completion of that course, he was stationed at Walter Reed Army Medical Center in Washington D.C. teaching surgical residents there and medical students from the Uniformed Services University of the Health Sciences and the George Washington University School of Medicine.

Collections of DeVries papers are held at the National Library of Medicine in Bethesda, Maryland.[15]

Media attention

Throughout his career, DeVries had to face a series of philosophical, religious, and practical objections to the artificial heart program. The media attention to the first implant was the largest ever directed to a medical case. Never before had a medical innovation aroused such a contentious debate.[8] Throughout the time between the implant and the death of Barney Clark, the media followed the case so intensively that teams of reporters and television crews besieged the medical center, hankering for information on the patient.[8] Criticism came not only from the medical world, but also from the public. Indeed, many people were disturbed by the idea of replacing the heart, considering it to have special and emotional meanings which could not be substituted by any human-made machine. The question asked by Una Loy, the wife of Barney Clark, is an example of this skepticism. Before her husband underwent surgery, she asked the doctor if after the transplant her husband would still be able to love her.[8] Many were also disturbed by the fact that Clark was never able to leave the hospital. His life was extended somewhat, but he spent it in bed. The New York Times questioned whether the artificial heart research was useful or just a "Dracula" sucking funds away from other programs.[8] DeVries felt that all this attention was slowing his work in Utah, and so decided to leave Salt Lake City for a position in Louisville.[7] Thanks to the Humana Inc. funds, DeVries implanted another artificial heart at the Humana Human Heart Institute International in a patient called Bill Schroeder. The whole case was followed by the media, and DeVries and the Humana were accused of publicity seeking; Life magazine called it "the Bill Schroeder's show". After the death of DeVries' second patient, the critics began to charge that the mechanical heart brought more complications than benefits. In fact, both Clark and Schroeder never fully recovered from the surgery and eventually died due to complications. DeVries felt that the best way to concede the dilemma was to have people understand that the TAH was not a permanent solution but just a temporary substitution for a diseased heart.

Publications

  • "Consumptive coagulopathy, shock, and the artificial heart." ; DeVries W.C., Kwan-Gett C.S., Kolff W.J. ; 1970 ; "American Society for Artificial Internal Organs" ; PMID 5454179
  • "Airway pressure and pulmonary edema formation." ; Alexander L.G., DeVries W.C., Anderson R.W. ; 1973 ; "Surgical Forum" ; PMID 4618644
  • "Pulmonary capillary filtration following oxygen exposure." ; DeVries W.C., Anderson R.W., Wolfe W.G., Alexander L.G. ; 1973 ; "Surgical Forum" ; PMID 4805992
  • "Ventilatory dead space in diagnosis of acute pulmonary embolism." ; Duranceau A., DeVries W.C., Wolfe W.G., Sabiston D.C. Jr. ; 1974 ; "Surgical Forum" ; PMID 4439171
  • "Changes in pulmonary capillary filtration and ventilatory dead space during exposure to 95 per cent oxygen." ; Wolfe W.G., Devries W.C., Anderson R.W., Sabiston D.C. Jr. ; April 1974 ; "The Journal of Surgical Research" ; PMID 4827935
  • "Oxygen toxicity." ; Wolfe W.G., DeVries W.C. ; 1975 ; "Annual Review of Medicine" ; PMID 807148
  • "Physiologic and pathologic responses of the pulmonary circulation to high flow shunts." ; DeVries W.C., Anderson R.W. ; 1975 ; "Surgical Forum" ; PMID 1216112
  • "Unilateral pulmonary emphysema created by ligation of the left pulmonary artery in newborn puppies." ; DeVries W.C., Seaber A.V., Sealy W.C. ; February 1979 ; "The Annals of Thoracic Surgery" ; PMID 453973
  • "Transvascular fluid and protein dynamics in the lung following hemorrhagic shock." ; Anderson R.W., DeVries W.C. ; April 1979 ; "The Journal of Surgical Research" ; PMID 933482
  • "Pulmonary tissue volume in isolated perfused dog lungs." ; Crapo R.O., Crapo J.D., Morris A.H., Berlin S.L., Devries W.C. ; May 1980 ; "Journal of Applied Physiology" ; PMID 7451289
  • "The management of spontaneous pneumothorax and bullous emphysema." ; DeVries W.C., Wolfe W.G. ; August 1980 ; "The Surgical Clinics of North America" ; PMID 7423365
  • "Artificial heart implantation, later cardiac transplantation in the calf." ; Olsen D.B., Devries W.C., Oyer P.E., Reitz B.A., Murashita J., Kolff W.J., Daitoh N., Jarvik R.K., Gaykowski R. ; 1981 ; "American Society for Internal Organs Journal" ; PMID 7036495
  • "Determinants of pannus formation in long-surviving artificial heart calves, and its prevention." ; Jarvik R.K., Kessler T.R., McGill L.D., Olsen D.B., DeVries W.C., Deneris J., Blaylock J.T., Kolff W.J. ; 1981 ; "American Society for Artificial Internal Organs" ; PMID 7331167
  • "Indeterminate circulatory support with the artificial heart." ; Olsen D.B., DeVries W.C., Kolff J., Frazier O.H., Rahimtoola S.H. ; 1982 ; "American Society for Artificial Internal Organs Journal" ; PMID 7164318
  • "Impact of regulations on artificial organs research." ; Morton W.A., DeVries W.C., Dobelle W.H., Serkes K.D., Sheridan R., Dennis C. ; 1983 ; "American Society for Artificial Internal Organs" ; PMID 6673323
  • "Response of the Human Body to the First Permanent Implant of the Jarvik-7 Total Artificial Heart" ; Joyce L.D., DeVries W.C., Hastings W.L., Olsen D.B., Jarvik R.K., Kolff W.J. ; 1983 ; "Transaction-American Society for Artificial Internal Organs" ; PMID 6673327
  • "The Artificial Heart" ; DeVries W.C., Joyce L.D. ; 1983 ; "Clinical Symposia" ; PMID 6546047
  • "Clinical Use of the Total Artificial Heart" ; William C. DeVries, M.D., Jeffrey L. Anderson, M.D., Lyle D. Joyce, M.D., Fred L. Anderson, M.D., Elizabeth H. Hammond, M.D., Robert K. Jarvik, M.D., and Willem J. Kolff, M.D., Ph.D. ; February 2, 1984; "The New England Journal of Medicine".
  • "Nutrition for the First Total Artificial Heart Patient: Implications for Future Patients" ; Raymond J., DeVries W.C., Joyce L.D. ; May 1984 ; "Journal of the American Dietetic Association" ; PMID 6425392
  • "Evaluation of Total Artificial Heart Performance in Man" ; Anderson F.L., DeVries W.C., Anderson J.L., Joyce L.D. ; August 1, 1984 ; "The American Journal of Cardiology" ; PMID 6465023
  • "Preparing an institution for clinical device experimentation." ; Hastings W.L., Mays J.B., Elzy P., DeVries W.C. ; 1985 ; "American Society for Artificial Internal Organs" ; PMID 3837541
  • "The ethical implications of the artificial heart: an interview with Dr. William DeVries." ; DeVries W.C. ; May–June 1985 ; "Federation of American Hospital" ; PMID 10271372
  • "The Role of Nuclear Imaging in the Management of the First Total Artificial Heart Recipient" ; Taylor A. Jr., Milton W., Christian P.E., Datz F.L., Joyce L., DeVries W.C. ; June 1985 ; "Clinical Nuclear Medicine" ; PMID 4017394
  • "Indexes of Hemolysis in Human Recipients of the Jarvik-7 Total Artificial Heart: a Cooperative Report of Fifteen Patients" ; Levinson M.M., Copeland J.G., Smith R.G., Cork R.C., DeVries W.C., Mays J.B., Griffith B.P., Kormos R., Joyce L.D., Pritzker M.R., et al. ; May–June 1986 ; "The Journal of Heart and Lung Transplantation" ; PMID 3612356
  • "Summary of the World Experience with Clinical use of Total Artificial Hearts as Heart Support Devices" ; Joyce L.D., Johnson K.E., Pierce W.S., DeVries W.C., Semb B.K., Copeland J.G., Griffith B.P., Cooley D.A., Frazier O.H., Cabrol C., et al. ; May–June 1986 ; "The Journal of Heart and Lung Transplantation" ; PMID 3302170
  • "Surgical Positioning of the Jarvik-7 Artificial Heart" ; Jarvik R.K., DeVries W.C., Semb B.K., Koul B., Copeland J.G., Levinson M.M., Griffith B.P., Joyce L.D., Cooley D.A., Frazier O.H., et al. ; May–June 1986 ; "The Journal of Heart and Lung Transplantation" ; PMID 3612355
  • "Results of artificial heart implantation in man." ; Yared S.F., Johnson G.S., DeVries W.C. ; June 1986 ; "Transplantation Proceedings-Journal" ; PMID 3521002
  • "Drive System Management of Emergency Conditions in Three Permanent Total Artificial Heart Patients" ; Mays J.B., Hastings W.L., Williams M.A., Barker L.E., DeVries W.C. ; July–September 1986 ; "American Society for Internal Organs Journal" ; PMID 3778716
  • "The Microscopic Evaluation of Skin Buttons used in a Long-Term Human Total Artificial Heart Recipient" ; Murray K.D., Abbott T., DeVries W.C., Gaykowski R., Olsen D.B. ; July–September 1986 ; "American Society for Internal Organs Journal" ; PMID 3778747
  • "Diagnostic monitoring and drive system management of patients with total artificial heart." ; Mays J.B., Williams M.A., Barker L.E., Hastings W.L., DeVries W.C. ; September 1986 ; "Heart and Lung: the Journal of Critical Care" ; PMID 3639075
  • "Atrial endocrine function in humans with artificial hearts." ; Schwab T.R., Edwards B.S., DeVries W.C., Zimmerman R.S., Burnett J.C. Jr. ; November 27, 1986 ; "The New England Journal of Medicine" ; PMID 2945989
  • "Vein graft arteriovenous fistula for long-term venous access in a heart transplant recipient lacking superficial veins: a case report." ; Girardet R.E., Masri Z.H., Barbie R.N., Attum A.A., Yared S., DeVries W.C., Lansing A.M. ; November–December 1986 ; "The Journal of Heart Transplantation" ; PMID 3302183
  • "Multigated Radionuclide Study of the Total Artificial Heart" ; Datz F.L., Christian P.E., Taylor A. Jr, Hastings W.L., DeVries W.C. ; 1987 ; "European Journal of Nuclear Medicine" ; PMID 3622562
  • "Thromboembolic and infectious complications of total artificial heart implantation." ; Ward R.A., Wellhausen S.R., Dobbins J.J., Johnson G.S., DeVries W.C. ; 1987 ; Division of Nephrology, School of Medicine, University of Louisville, Kentucky ; "Annals of the New York Academy of Science" ; PMID 3439750
  • "Alterations in select immunologic parameters following total artificial heart implantation." ; Stelzer GT, Ward RA, Wellhausen SR, McLeish KR, Johnson GS, DeVries WC. ; February 1987 ; "Artificial Organs" ; PMID 3566584
  • "A clinical estimation model for noninvasive determination of atrial pressure in total artificial heart patients." ; Mays J.B., Williams M.A., Jung S., Frederick M.G., Barker L.E., DeVries W.C. ; July–September 1987 ; Humana Heart Institute International, Louisville, KY ; "American Society of Artificial Internal Organs" ; PMID 3676010
  • "Postmortem microbiological findings of two total artificial heart recipients." ; Dobbins J.J., Johnson G.S., Kunin C.M., DeVries W.C. ; February 1988 ; Beliamine College, Louisville, KY ; "The Journal of the American Medical Association" ; PMID 3121874
  • "Surgical technique for implantation of the Jarvik-7-100 total artificial heart." ; DeVries W.C. ; February 1988 ; Humana Heart Institute International, Louisville, KY ;"The Journal of the American Medical Association" ; PMID 3275826
  • "Biomaterial-centered sepsis and the total artificial heart. Microbial adhesion vs tissue integration." ; Gristina A.G., Dobbins J.J., Giammara B., Lewis J.C., DeVries W.C. ; February 12, 1988 ; Section of Orthopedic Surgery, Wake Forest University Medical Center, Winston-Salem, NC ; "The Journal of the American Medical Association" ; PMID 3336200
  • "The permanent artificial heart. Four case reports." ; DeVries W.C. ; February 12, 1988 ; Humana Heart Institute International, Louisville, KY ; "The Journal of the American Medical Association" ; PMID 3336198
  • "The physician, the media, and the 'spectacular' case." ; DeVries W.C. ; February 12, 1988 ; Humana Heart Institute International, Louisville, KY ; "The Journal of the American Medical Association" ; PMID 3275827
  • "Immunologic complications of long-term implantation of a total artificial heart." ; Wellhausen S.R., Ward R.A., Johnson G.S., DeVries W.C. ; July 1988 ; Division of Nephrology, School of Medicine, University of Louisville, Kentucky ; "Journal of Clinical Immunology" ; PMID 3261735
  • "The Role of Nuclear Medicine in Three Permanent Total Artificial Heart Recipients" ; Zenger G.H., DeVries W.C. ; July 1988 ; Humana Heart Institute International, Louisville, KY ; "Seminars in Nuclear Medicine" ; PMID 3175681
  • "Nine Year Experience with the Clinical use of Total Artificial Hearts as Cardiac Support Devices" ; Joyce L.D., Johnson K.E., Cabrol C., Griffith B.P., Copeland J.G., DeVries W.C., Keon W.J., Wolner E., Frazier O.H., Bucherl E.S., et al. ; July–September 1988 ; Minneapolis Heart Institute ; "American Society for Internal Organs Journal" ; PMID 3058184
  • "Circulatory Support 1988. Bleeding and Anticoagulation" ; Jack G. Copeland III, Laurence A. Harker, J. Heinrich Joist, and William C. DeVries ; January 1989 ; "The Annals of Thoracic Surgery" ; PMID 2912399
  • "Cardiorespiratory Interactions in Aatients with an Artificial Heart" ; Robotham J.L., Mays J.B., Williams M.A., DeVries W.C. ; October 1990 ; Department of Anesthesiology and Critical Care, Johns Hopkins Hospital, Baltimore, Maryland ; "Anesthesiology: The Journal of the American Society of Anestesiologists, Inc."
  • "Repair of Anomalous Origin of Right Coronary Artery from the Left Sinus of Valsalva" ; Houman Tavaf-Motamen, Sean P. Bannister, Philip C. Corcoran, Robert W. Stewart, Charles R. Mulligan, and William C. DeVries ; June 2008 ; Division of Cardiothoracic Surgery, Walter Reed Army Medical Center, Washington DC ; "The Annals of Thoracic Surgery"
  • "Chondrosarcoma Masquerading as Cardiomyopathy" ; Charles R. Mulligan Jr, Houman Tavaf-Motamen, Robert Stewart, and William C. Devries ; July 2008 ; Division of Cardiothoracic Surgery, Walter Reed Army Medical Center, Washington DC ; "The Annals of Thoracic Surgery"
  • "Who was William Ray Rumel?" ; Welling D.R., Rich N.M., Burris D.G., Boffard K.D., Devries W.C. ; September 2008 ; "World Journal of Surgery" ; PMID 18443854

Further reading

References

  1. ^ a b Kozaryn, Linda D. (2002). "Dr. Willilam C. DeVries, Surgeon". Defend America. Archived from the original on January 5, 2014. Retrieved June 12, 2006.
  2. ^ David K.C. Cooper."Open Heart: The Radical Surgeons who Revolutionized Medicine." 2010, New York, Kaplan Publishing.ISBN 978-1-60714-490-8; pag 389
  3. ^ "Fact Sheet Eagle Scouts". Boy Scouts of America. Archived from the original on February 27, 2008. Retrieved March 3, 2008.
  4. ^ a b c d e f Webster, Bayard (December 3, 1982). "Men in the News; a Pair of Skilled Hands to Guide an Artificial Heart: Robert Kiffler Jarvik". The New York Times. Retrieved November 15, 2012.
  5. ^ David K.C. Cooper."Open Heart: The Radical Surgeons who Revolutionized Medicine." 2010, New York, Kaplan Publishing.ISBN 978-1-60714-490-8; pag 390
  6. ^ David K.C. Cooper."Open Heart: The Radical Surgeons who Revolutionized Medicine." 2010, New York, Kaplan Publishing.ISBN 978-1-60714-490-8; pag 390-391
  7. ^ a b c d e "William Castle DeVries Biography". Encyclopedia of World Biography. Retrieved November 19, 2012.
  8. ^ a b c d e Jauhar, Sandeep (February 5, 2004). "The Artificial Heart". The New England Journal of Medicine. 350 (6): 542–544. doi:10.1056/NEJMp038244. PMID 14762180.
  9. ^ DeVries, William C.; Anderson, Jeffery L.; Joyce, Lyle D.; Anderson, Fred L.; Hammond, Elizabeth H.; Jarvik, Robert K.; Kloff, Williem J. (February 2, 1984). "Clinical Use of the Total Artificial Heart". The New England Journal of Medicine. 310 (5): 273–278. doi:10.1056/NEJM198402023100501. PMID 6690950.
  10. ^ David K.C. Cooper."Open Heart: The Radical Surgeons who Revolutionized Medicine." 2010, New York, Kaplan Publishing.ISBN 978-1-60714-490-8; pag 389-393
  11. ^ a b c Heart, Jarvik. "Robert Jarvik on the Jarvik-7". Jarvik Heart. Archived from the original on January 20, 2013. Retrieved November 19, 2012.
  12. ^ "Conversione unità di misura". www.dossier.net.
  13. ^ David K.C. Cooper."Open Heart: The Radical Surgeons who Revolutionized Medicine." 2010, New York, Kaplan Publishing.ISBN 978-1-60714-490-8; pag 391
  14. ^ "Golden Plate Awardees of the American Academy of Achievement". www.achievement.org. American Academy of Achievement.
  15. ^ "William C. DeVries Papers 1946-2002". National Library of Medicine.

Sources

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