To install click the Add extension button. That's it.

The source code for the WIKI 2 extension is being checked by specialists of the Mozilla Foundation, Google, and Apple. You could also do it yourself at any point in time.

4,5
Kelly Slayton
Congratulations on this excellent venture… what a great idea!
Alexander Grigorievskiy
I use WIKI 2 every day and almost forgot how the original Wikipedia looks like.
Live Statistics
English Articles
Improved in 24 Hours
Added in 24 Hours
What we do. Every page goes through several hundred of perfecting techniques; in live mode. Quite the same Wikipedia. Just better.
.
Leo
Newton
Brights
Milds

Wayne L. Hubbell

From Wikipedia, the free encyclopedia

Wayne L. Hubbell
Born (1943-03-24) March 24, 1943 (age 81)
NationalityAmerican
EducationOregon State University, B.S. 1965: Stanford University (Ph.D. 1970); Stanford University (Postdoctoral Fellow)
Known forSite-directed spin labeling
AwardsNational Academy of Sciences
Scientific career
FieldsBiochemistry of vision
InstitutionsUniversity of California, Los Angeles
Doctoral studentsLinda Columbus

Wayne L. Hubbell (born 24 March 1943) is an American biochemist and member of the National Academy of Sciences. He is Professor of Biochemistry and Jules Stein Professor of Ophthalmology at the University of California, Los Angeles. His research focuses on the visual system, and is primarily supported by a grant from the National Eye Institute.[citation needed]

YouTube Encyclopedic

  • 1/1
    Views:
    502 108
  • Well Pressure Switches

Transcription

Research

Dr. Hubbell has studied the relationship between the molecular structure of protein and the conformational changes that control its function. Of particular interest are membrane proteins that behave as "molecular switches", i.e., proteins whose structures are switched to an active state by a physical or chemical signals. An example is light-activated rhodopsin, the visual pigment in photoreceptor cells of the retina. The goal is to elucidate the structure of rhodopsin, the mechanism of the molecular switch, and regulation of this switch by associated proteins, transducin and arrestin.

Dr. Hubbell's research also includes structure and function relationships in water-soluble proteins such as the lens protein, a-crystallin, and the retinoid carrying proteins which transport vitamin A throughout photoreceptor cells.

Dr. Hubbell's laboratory developed site-directed spin labeling (SDSL), a technique for the exploration of protein structure and dynamics. By changing the genetic code, a specific attachment point in the protein is created for a nitroxide spin label probe. Analysis of the electron paramagnetic resonance (EPR) spectrum of the spin label provides information about the local environment in the protein. With a sufficiently large set of labeled proteins, global information on structure is obtained, and most importantly, changes in the structure during function can be followed in real time.

Education and training

Awards and honors

References

  • "Wayne L. Hubbell Summary". UCLA Department of Chemistry and Biochemistry. Retrieved 2006-12-07.
  • "Hubbell, Wayne L." National Academy of Sciences Membership Directory. Retrieved 2006-12-07.
  • "Biochemist joins National Academy of Sciences". Ophthalmology Times. 2005-08-01. Retrieved 2006-12-07.
  • "Highlights of the Year, 2004-2005" (PDF). Jules Stein Eye Institute. Retrieved 2006-12-08.
  • "Teacher-Scholars 1970–1996, A Retrospective" (PDF). The Camille and Henry Dreyfus Foundation. Archived from the original (PDF) on 2006-10-06. Retrieved 2006-12-08.

External links

This page was last edited on 19 May 2023, at 04:17
Basis of this page is in Wikipedia. Text is available under the CC BY-SA 3.0 Unported License. Non-text media are available under their specified licenses. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc. WIKI 2 is an independent company and has no affiliation with Wikimedia Foundation.