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Toxopyrimidine

From Wikipedia, the free encyclopedia

Toxopyrimidine
Names
Preferred IUPAC name
(4-Amino-2-methylpyrimidin-5-yl)methanol
Other names
Pyramin[1]
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.234.283 Edit this at Wikidata
UNII
  • InChI=1S/C6H9N3O/c1-4-8-2-5(3-10)6(7)9-4/h2,10H,3H2,1H3,(H2,7,8,9)
    Key: VUTBELPREDJDDH-UHFFFAOYSA-N
  • Cc1ncc(c(n1)N)CO
Properties
C6H9N3O
Molar mass 139.158 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Toxopyrimidine is a vitamin B6 antagonist with potent convulsant effects.[2][3]

See also

References

  1. ^ Haughton BG, King HK (December 1958). "Toxo-pyrimidine phosphate as an inhibitor of bacterial enzyme systems that require pyridoxal phosphate". The Biochemical Journal. 70 (4): 660–5. doi:10.1042/bj0700660. PMC 1196724. PMID 13607425.
  2. ^ Rindi G, Ferrari G (February 1959). "The gamma-aminobutyric acid and glutamic acid content of brains of rats treated with toxopyrimidine". Nature. 183 (4661): 608–9. Bibcode:1959Natur.183..608R. doi:10.1038/183608a0. PMID 13632808. S2CID 4200644.
  3. ^ Rindi G, Perri V, Ventura U (April 1959). "Effect of toxopyrimidine on glutamic-decarboxylase and glutamic-oxalacetic transaminase of rat brain". Nature. 183 (4668): 1126–7. Bibcode:1959Natur.183.1126R. doi:10.1038/1831126a0. PMID 13657025. S2CID 4209134.

External links


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This page was last edited on 28 September 2022, at 00:40
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