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Tripartite motif-containing protein 16 is a protein that in humans is encoded by the TRIM16gene.[4][5]
This gene was identified as an estrogen and anti-estrogen regulated gene in epithelial cells stably expressing estrogen receptor. The protein encoded by this gene contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family.
The proteins of this family have been reported to be involved in a variety of biological processes including cell growth, differentiation and pathogenesis. Expression of this gene was detected in most tissues. Its function, however, has not yet been determined.[5]
Munding C, Keller M, Niklaus G, et al. (2006). "The estrogen-responsive B box protein: a novel enhancer of interleukin-1beta secretion". Cell Death Differ. 13 (11): 1938–49. doi:10.1038/sj.cdd.4401896. PMID16575408. S2CID8953820.
This page was last edited on 6 January 2024, at 05:11