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Putative tyrosine-protein phosphatase TPTE is an enzyme that in humans is encoded by the TPTEgene.[3][4]
Function
TPTE is a member of a large class of membrane-associated phosphatases with substrate specificity for the 3-position phosphate of inositolphospholipids.[4] TPTE is a primate-specific duplicate of the TPTE2 (TPIP) inositol phospholipid phosphatase;[5] TPTE itself is predicted to lack phosphatase activity.[6] TPTE and TPTE2 are the mammalian homologues to the subfamily of voltage sensitive phosphatases.
Antonarakis SE (1998). "10 years of Genomics, chromosome 21, and Down syndrome". Genomics. 51 (1): 1–16. doi:10.1006/geno.1998.5335. PMID9693027.
Chen H, Rossier C, Morris MA, et al. (2000). "A testis-specific gene, TPTE, encodes a putative transmembrane tyrosine phosphatase and maps to the pericentromeric region of human chromosomes 21 and 13, and to chromosomes 15, 22, and Y.". Hum. Genet. 105 (5): 399–409. doi:10.1007/s004390051122. PMID10598804.
This page was last edited on 18 October 2023, at 21:27