Succinyldiaminopimelate transaminase

In enzymology, a succinyldiaminopimelate transaminase (EC 2.6.1.17) is an enzyme that catalyzes the chemical reaction

N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate ${\displaystyle \rightleftharpoons }$ N-succinyl-L-2-amino-6-oxoheptanedioate + L-glutamate

Thus, the two substrates of this enzyme are N-succinyl-L-2,6-diaminoheptanedioate and 2-oxoglutarate, whereas its two products are N-succinyl-L-2-amino-6-oxoheptanedioate and L-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is N-succinyl-L-2,6-diaminoheptanedioate:2-oxoglutarate aminotransferase. Other names in common use include succinyldiaminopimelate aminotransferase, and N-succinyl-L-diaminopimelic glutamic transaminase. This enzyme participates in lysine biosynthesis. It employs one cofactor, pyridoxal phosphate.

References

• Peterkofsky B, Gilvarg C (May 1961). "N-Succinyl-L-diaminopimelic-glutamic transaminase". The Journal of Biological Chemistry. 236: 1432–8. PMID 13734750.

This page was last edited on 26 August 2023, at 15:55