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Spirendolol

From Wikipedia, the free encyclopedia

Spirendolol
Names
IUPAC name
4-[3-(tert-Butylamino)-2-hydroxypropoxy]spiro[3H-indene-2,1'-cyclohexane]-1-one
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C21H31NO3/c1-20(2,3)22-13-15(23)14-25-18-9-7-8-16-17(18)12-21(19(16)24)10-5-4-6-11-21/h7-9,15,22-23H,4-6,10-14H2,1-3H3
    Key: YLBMSIZZTJEEIO-UHFFFAOYSA-N
  • InChI=1/C21H31NO3/c1-20(2,3)22-13-15(23)14-25-18-9-7-8-16-17(18)12-21(19(16)24)10-5-4-6-11-21/h7-9,15,22-23H,4-6,10-14H2,1-3H3
    Key: YLBMSIZZTJEEIO-UHFFFAOYAB
  • CC(C)(C)NCC(COC1=CC=CC2=C1CC3(C2=O)CCCCC3)O
Properties
C21H31NO3
Molar mass 345.483 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Spirendolol is a beta adrenergic receptor antagonist.[1]

References

  1. ^ Mostaghim, R; Maddox, YT; Ramwell, PW (1986). "Endothelial potentiation of relaxation response to beta adrenoceptor blocking agents". The Journal of Pharmacology and Experimental Therapeutics. 239 (3): 797–801. PMID 2879033.



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This page was last edited on 16 April 2022, at 15:05
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