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Sabyasachi Sarkar

From Wikipedia, the free encyclopedia

Sabyasachi Sarkar
সব্যসাচী সরকার
Prof. Sabyasachi Sarkar.jpg
Born17 May 1947 (1947-05-17) (age 74)
Jamtara, India
Alma materRamakrishna Mission Vidyamandira, Rajabazar Science College, University of Calcutta, Gorakhpur University
Scientific career
FieldsBio inorganic chemistry, nano science
InstitutionsIIT Kanpur
Indian Institute of Engineering Science and Technology, Shibpur

Sabyasachi Sarkar[1] (born 17 May 1947) is an Indian chemist. He has worked with functional models related to hyperthermophilic to mesophilic metalloproteins enriching bioinorganic chemistry.[2][3][4][5][6][7] A Replica of a Fishy Enzyme[8] and the reduced xanthine oxidase[9] also have been made. Inhibition patterns[10] in the Michaelis complex of low molecular weight hepatic sulfite oxidase model complex have been exhibited.[11] Based on functional mimicking of a series of molybdoenzymes he showed that the even in model enzymatic oxotransfer reactions the participation of similar enzyme-susbrate (E-S) complex is a real entity. Such a chemical spices (E-S) responds to spontaneous intramolecular oxidative addition and reductive elimination to complete the oxotransfer reaction. Such a reaction differs from conventional chemical oxotransfer reaction where the reaction between the starting reactants happens in Eyring activated complex.[12] He demonstrated that carbon dioxide molecule does bind to magnesium in chlorophyll[13] in photosynthesis as proposed by R. M. Willstätter one-hundred years ago and modeled hydrogenase captioned as better than nature.[14] The rare reaction of a Cu(II) complex with aerial oxygen to generate superoxide anion and Cu(III) has been shown addressing the native SOD reaction.[15] Similarly the aspect of copper-molybdenum antagonism in ruminant animals have been investigated.[16] His research has shown the architectural marvel in silk cocoon with the natural thermostatic and humidity control with preferential oxygen gating inside cocoon as green house architecture.[17] He proposed a new magneto reception mechanism for nocturnal moth in sensing the Earth's magnetic field to navigate with a stable pool of carbon-centric free radicals along with ferromagnetic components.[18] He extended the work on nano carbon[19] and developed cheap sources of water soluble nano carbon including naturally formed graphene oxide from low grade coal.[20] These are used in the growth of young plants as promoters to slowly release micro nutrients and adsorbed water.[21][22][23][24] He explored these to explore bio-imaging[25] and demonstrating that non-toxic carbon nano onion[26][27] can cross blood–brain barrier[28] to carry drug as cargo and can be effectively be excreted from the body. The utility of such nano carbon to control mosquito breeding in preventing mosquito vectors of infectious diseaes[29] and the use of reduced graphene oxide to prevent hospital pathogens have been demonstrated.[30] On the environment aspect the presence of damaged floating carbon nano tubes in aerosols is shown to contribute global warming, winter smog and elevating breathing problem.[31] He demonstrated the adverse effect of soap and detergent discharge near tube wells in releasing arsenic and fluoride contaminated water.[32] He also mapped the degradation of a heritage monument, the Taj Mahal.[33]

Early life and education

Prof. Sabysachi Sarkar hails from the family of legal advisor of the local king was born in Birbhum (meaning forest land) district, West Bengal in the Zaminder house of his maternal grandparent. His early education came from St. Xavier's College and Ramakrishna Mission Vidyamandira, Belurmath. He did a M.Sc. from the prestigious Rajabazar Science College, University of Calcutta at the age of 19.[34] He is the lone living grad student of Acharya Prafulla Chandra Ray as practicing chemist even today. He started his research under Professor Pulin Behari Sarkar in the Rajabazar Science College. After learning analytical-inorganic chemistry he learnt thermodynamics from Professor R.P Rastogi of Gorakhpur University. He pursued aggregates of metal oxides and sulfides of diverse interest from the school of Professor Achim Müller in Germany. He practiced research in diversified field of interest including environment, healthcare science, and conservation.

Professional life


State, National, CSIR, Indian Chemical Society, INSA Research, Academy of Science, Humboldt, DAAD, Raja Ramanna, Royal Society of Chemistry.


Professor R.K. Barua Memorial Lecture; Professor R. D. Desai Medal and Prize; Professor Priyadaranjan Ray Memorial Award; Honorary Professor, Faculty of Science –BHU; Annual Professor Sabyasachi Sarkar endowment lecture at RKM Vidyamandira. Belurmath instituted by former PhD student. Honorary Professor Emeritus, IIEST-Shibpur.

Literary work

He writes satire on Indian science and other science-based articles in Bengali magazines. His full list of writing are available at his website.


  1. ^ "Sabyasachi Sarkar". ResearchGate. Retrieved 25 March 2016.
  2. ^ Sarkar, Sabyasachi; Das, Samar K. (August 1992). "CO2 fixation by [WIVO(S2C2(CN)2)2]2−: functional model for the tungsten-formate dehydrogenase of Clostridium thermoaceticum". Proceedings of the Indian Academy of Sciences – Chemical Sciences. 104: 533–534. doi:10.1007/BF02840500 (inactive 31 May 2021). Retrieved 25 March 2016.CS1 maint: DOI inactive as of May 2021 (link)
  3. ^ Das, Samar K.; Chaudhury, Pradeep K.; Biswas, Dulali; Sarkar, Sabyasachi (1 May 2002). "Modeling for the Active Site of Sulfite Oxidase: Synthesis, Characterization, and Reactivity of [MoVIO2(mnt)2]2- (mnt2- = 1,2-Dicyanoethylenedithiolate)". Journal of the American Chemical Society. 116 (20): 9061–9070. doi:10.1021/ja00099a024.
  4. ^ Das, Samar K.; Biswas, Dulali; Maiti, Rabindranath; Sarkar, Sabyasachi (14 February 1996). "Modeling the Tungsten Sites of Inactive and Active Forms of Hyperthermophilic Pyrococcus furiosus Aldehyde Ferredoxin Oxidoreductase". Journal of the American Chemical Society. 118 (6): 1387–1397. doi:10.1021/ja9511580.
  5. ^ Yadav, Jyoti; Das, Samar K.; Sarkar, Sabyasachi (7 May 1997). "A Functional Mimic of the New Class of Tungstoenzyme, Acetylene Hydratase". Journal of the American Chemical Society. 119 (18): 4315–4316. doi:10.1021/ja970134l.
  6. ^ Prasad, Rishitosh; Sarkar, Sabyasachi (November 1997). "Evolutionary extremophilic Archaeal domain of life" (PDF). Current Science. 73 (10): 842–854. Retrieved 26 March 2016.
  7. ^ Majumdar, Amit; Pal, Kuntal; Sarkar, Sabyasachi (11 March 2006). "Chemistry of [Et 4 N] [Mo IV (SPh) (PPh 3) (mnt) 2] as an Analogue of Dissimilatory Nitrate Reductase with Its Inactivation on Substitution of Thiolate by Chloride". Journal of the American Chemical Society. 128 (13): 4196–4197. doi:10.1021/ja0586135. PMID 16568972.
  8. ^ Moula, Golam; Bose, Moumita; Sarkar, Sabyasachi (17 April 2013). "Replica of a Fishy Enzyme: Structure–Function Analogue of Trimethylamine-N-Oxide Reductase". Inorganic Chemistry. 52 (9): 5316–5327. doi:10.1021/ic4002576. PMID 23594155.
  9. ^ Mitra, Joyee; Sarkar, Sabyasachi (5 February 2013). "Modelling the reduced xanthine oxidase in active sulfo and inactive desulfo forms". Dalton Transactions. 42 (9): 3050–3058. doi:10.1039/c2dt32309e. PMID 23299556.
  10. ^ Chaudhury, P K; Das, S K; Sarkar, S (1 November 1996). "Inhibition patterns of a model complex mimicking the reductive half-reaction of sulphite oxidase". Biochemical Journal. 319 (Pt 3): 953–959. doi:10.1042/bj3190953. ISSN 0264-6021. PMC 1217881. PMID 8921005.
  11. ^ Pal, Kuntal; Chaudhury, Pradeep K.; Sarkar, Sabyasachi (3 August 2007). "Structure of the Michaelis Complex and Function of the Catalytic Center in the Reductive Half-Reaction of Computational and Synthetic Models of Sulfite Oxidase". Chemistry: An Asian Journal. 2 (8): 956–964. doi:10.1002/asia.200700020. ISSN 1861-471X. PMID 17600788.
  12. ^ Pakhira, Bholanath; Sarkar, Rudra; Sarkar, Sabyasachi (29 September 2016). "Chapter 3:Electron Transfer Mechanisms in Molybdenum and Tungsten Model Compounds". Molybdenum and Tungsten Enzymes. Metallobiology. pp. 68–93. doi:10.1039/9781782628828-00068. ISBN 978-1-78262-877-4.
  13. ^ Bhuyan, Jagannath; Sarkar, Rudra; Sarkar, Sabyasachi (4 November 2011). "A Magnesium Porphyrin Bicarbonate Complex with CO2-Modulated Photosystem I Action". Angewandte Chemie International Edition. 50 (45): 10603–10607. doi:10.1002/anie.201103876. ISSN 1521-3773. PMID 21932225.
  14. ^ Begum, Ameerunisha; Sarkar, Sabyasachi (1 January 2012). "An Iron(III) Dithiolene Complex as a Functional Model of Iron Hydrogenase". European Journal of Inorganic Chemistry. 2012 (1): 40–43. doi:10.1002/ejic.201100879. ISSN 1099-0682.
  15. ^ Bhattacharya, Dibyendu; Maji, Suman; Pal, Kuntal; Sarkar, Sabyasachi (1 May 2008). "Formation of Superoxide Anion on Aerial Oxidation of Cu(II)–Porphyrinogen in the Synthesis of Tetrakis(cyclohexyl)porphyrinogenCu(III) Anion". Inorganic Chemistry. 47 (12): 5036–5038. doi:10.1021/ic800282j. PMID 18447338.
  16. ^ Sarkar, S.; Mishra, S. B. S. (1 September 1984). "Synthetic aspects of CuMos systems and their possible relevance to copper—molybdenum antagonism". Coordination Chemistry Reviews. 59: 239–264. doi:10.1016/0010-8545(84)85056-0.
  17. ^ Roy, Manas; Meena, Sunil Kumar; Kusurkar, Tejas Sanjeev; Singh, Sushil Kumar; Sethy, Niroj Kumar; Bhargava, Kalpana; Sarkar, Sabyasachi; Das, Mainak (1 December 2012). "Carbondioxide Gating in Silk Cocoon". Biointerphases. 7 (1): 45. doi:10.1007/s13758-012-0045-7. ISSN 1934-8630. PMID 22791361. S2CID 5742774.
  18. ^ Roy, Manas; Kusurkar, Tejas Sanjeev; Maurya, Sandeep Kumar; Meena, Sunil Kumar; Singh, Sushil Kumar; Sethy, Niroj; Bhargava, Kalpana; Sharma, Raj Kishore; Goswami, Debabrata (24 March 2013). "Graphene oxide from silk cocoon: a novel magnetic fluorophore for multi-photon imaging". 3 Biotech. 4 (1): 67–75. doi:10.1007/s13205-013-0128-2. ISSN 2190-572X. PMC 3909567. PMID 28324464.
  19. ^ Dubey, Prashant; Muthukumaran, Devarajan; Dash, Subhashis; Mukhopadhyay, Rupa; Sarkar, Sabyasachi (1 October 2005). "Synthesis and characterization of water-soluble carbon nanotubes from mustard soot". Pramana. 65 (4): 681–697. Bibcode:2005Prama..65..681D. doi:10.1007/BF03010456. ISSN 0304-4289. S2CID 53490874.
  20. ^ Pakhira, Bholanath; Ghosh, Subrata; Maity, Sheli; Sangeetha, D. N.; Laha, Ankita; Allam, Afreen; Sarkar, Sabyasachi (19 October 2015). "Extraction of preformed graphene oxide from coal: its clenched fist form entrapping large molecules". RSC Adv. 5 (108): 89076–89082. Bibcode:2015RSCAd...589076P. doi:10.1039/c5ra15699h.
  21. ^ Tripathi, Shweta; Sonkar, Sumit Kumar; Sarkar, Sabyasachi (10 March 2011). "Growth stimulation of gram (Cicer arietinum) plant by water soluble carbon nanotubes". Nanoscale. 3 (3): 1176–1181. Bibcode:2011Nanos...3.1176T. doi:10.1039/c0nr00722f. PMID 21253651.
  22. ^ Sonkar, Sumit Kumar; Roy, Manas; Babar, Dipak Gorakh; Sarkar, Sabyasachi (26 November 2012). "Water soluble carbon nano-onions from wood wool as growth promoters for gram plants". Nanoscale. 4 (24): 7670–7675. Bibcode:2012Nanos...4.7670S. doi:10.1039/c2nr32408c. PMID 23099536.
  23. ^ Saxena, Manav; Maity, Sheli; Sarkar, Sabyasachi (September 2014). "Carbon nanoparticles in 'biochar' boost wheat (Triticum aestivum) plant growth". RSC Adv. 4 (75): 39948–39954. Bibcode:2014RSCAd...439948S. doi:10.1039/c4ra06535b.
  24. ^ Tripathi, Shweta; Sarkar, Sabyasachi (9 September 2014). "Influence of water soluble carbon dots on the growth of wheat plant". Applied Nanoscience. 5 (5): 609–616. doi:10.1007/s13204-014-0355-9. ISSN 2190-5509. S2CID 137168230.
  25. ^ Ghosh, Mitrajit; Sonkar, Sumit Kumar; Saxena, Manav; Sarkar, Sabyasachi (18 November 2011). "Carbon Nano-onions for Imaging the Life Cycle of Drosophila Melanogaster". Small. 7 (22): 3170–3177. doi:10.1002/smll.201101158. ISSN 1613-6829. PMID 22012886.
  26. ^ Sonkar, Sumit Kumar; Roy, Manas; Babar, Dipak Gorakh; Sarkar, Sabyasachi (26 November 2012). "Water soluble carbon nano-onions from wood wool as growth promoters for gram plants". Nanoscale. 4 (24): 7670–7675. Bibcode:2012Nanos...4.7670S. doi:10.1039/c2nr32408c. PMID 23099536.
  27. ^ Sonkar, Sumit Kumar; Ghosh, Mitrajit; Roy, Manas; Begum, Ameerunisha; Sarkar, Sabyasachi (1 June 2012). "Carbon Nano-Onions as Nontoxic and High-Fluorescence Bioimaging Agent in Food Chain—An In Vivo Study from Unicellular E. coli to Multicellular C. elegans". Materials Express. 2 (2): 105–114. doi:10.1166/mex.2012.1064.
  28. ^ Pakhira, Bholanath; Ghosh, Mitrajit; Allam, Afreen; Sarkar, Sabyasachi (21 March 2016). "Carbon nano onions cross the blood brain barrier". RSC Adv. 6 (35): 29779–29782. Bibcode:2016RSCAd...629779P. doi:10.1039/c5ra23534k.
  29. ^ Saxena, Manav; Sonkar, Sumit Kumar; Sarkar, Sabyasachi (21 October 2013). "Water soluble nanocarbons arrest the growth of mosquitoes". RSC Advances. 3 (44): 22504–22508. Bibcode:2013RSCAd...322504S. doi:10.1039/c3ra44100h.
  30. ^ Dutta, Taposhree; Sarkar, Rudra; Pakhira, Bholanath; Ghosh, Subrata; Sarkar, Ripon; Barui, Ananya; Sarkar, Sabyasachi (21 September 2015). "ROS generation by reduced graphene oxide (rGO) induced by visible light showing antibacterial activity: comparison with graphene oxide (GO)". RSC Adv. 5 (98): 80192–80195. Bibcode:2015RSCAd...580192D. doi:10.1039/c5ra14061g.
  31. ^ Banerjee, Saumyabrata; Tripathi, Sachchida N.; Das, Utpal; Ranjan, Raju; Jadhav, Nilesh; Singh, Vivek P.; Jariwala, Chinmay; Sonkar, Sumit; Sarkar, Sabyasachi (15 July 2012). "Enhanced persistence of fog under illumination for carbon nanotube fog condensation nuclei". Journal of Applied Physics. 112 (2): 024901–024901–4. Bibcode:2012JAP...112b4901B. doi:10.1063/1.4736557. ISSN 0021-8979.
  32. ^ Dey, Soumen; Chatterjee, Shahana; Sarkar, Sabyasachi (10 December 2005). "Direct and indirect arsenic release from soaps by unhygienic use in tubewells" (PDF). Current Science.
  33. ^ Samadhiya, N.K.; Banerjee, Deepankar; Sarkar, Sabyasachi (2009). Jain, K.K. (ed.). Characterization of the dust in the ambience of the Taj Mahal, Agra. Agam Kala Prakashan. pp. 25–30.
  34. ^ "Reminiscence:Santhal Parganas to Chemistry".

External links

This page was last edited on 3 June 2021, at 15:54
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