To install click the Add extension button. That's it.

The source code for the WIKI 2 extension is being checked by specialists of the Mozilla Foundation, Google, and Apple. You could also do it yourself at any point in time.

How to transfigure the Wikipedia

Would you like Wikipedia to always look as professional and up-to-date? We have created a browser extension. It will enhance any encyclopedic page you visit with the magic of the WIKI 2 technology.

Try it — you can delete it anytime.

Install in 5 seconds
4,5
Kelly Slayton
Congratulations on this excellent venture… what a great idea!
Alexander Grigorievskiy
I use WIKI 2 every day and almost forgot how the original Wikipedia looks like.
What we do. Every page goes through several hundred of perfecting techniques; in live mode. Quite the same Wikipedia. Just better.
Great Wikipedia has got greater.
.
Leo
Newton
Brights
Milds

Phenylhydrazine

From Wikipedia, the free encyclopedia

Phenylhydrazine[1][2]
Phenylhydrazine
Ball-and-stick model of phenylhydrazine
Ball-and-stick model of phenylhydrazine
Space-filling model of phenylhydrazine
Space-filling model of phenylhydrazine
Names
Preferred IUPAC name
Phenylhydrazine
Other names
Hydrazinobenzene
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.002.612 Edit this at Wikidata
KEGG
UNII
  • InChI=1S/C6H8N2/c7-8-6-4-2-1-3-5-6/h1-5,8H,7H2 checkY
    Key: HKOOXMFOFWEVGF-UHFFFAOYSA-N checkY
  • InChI=1/C6H8N2/c7-8-6-4-2-1-3-5-6/h1-5,8H,7H2
    Key: HKOOXMFOFWEVGF-UHFFFAOYAN
  • NNc1ccccc1
Properties
C6H5NHNH2
Molar mass 108.144 g·mol−1
Appearance Colorless to pale-yellow liquid or solid[3]
Odor faint, aromatic[3]
Density 1.0978 g/cm3
Melting point 19.5 °C (67.1 °F; 292.6 K) (24 °C for hemihydrate)
Boiling point 243.5 °C (470.3 °F; 516.6 K) (decomposition)
Vapor pressure 0.04 mmHg (25°C)[3]
-67.82·10−6 cm3/mol
Hazards
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 3: Short exposure could cause serious temporary or residual injury. E.g. chlorine gasFlammability 2: Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur. Flash point between 38 and 93 °C (100 and 200 °F). E.g. diesel fuelInstability 3: Capable of detonation or explosive decomposition but requires a strong initiating source, must be heated under confinement before initiation, reacts explosively with water, or will detonate if severely shocked. E.g. hydrogen peroxideSpecial hazards (white): no code
3
2
3
Flash point 88 °C; 190 °F; 361 K[3]
Lethal dose or concentration (LD, LC):
  • 188 mg/kg (rat, oral)
  • 175 mg/kg (mouse, oral)
  • 80 mg/kg (rabbit, oral)
  • 80 mg/kg (guinea pig, oral)
  • 200-250 mg/kg (dog, oral)
[4]
NIOSH (US health exposure limits):
PEL (Permissible)
 TWA 5 ppm (22 mg/m3) [skin][3]
REL (Recommended)
 Ca C 0.14 ppm (0.6 mg/m3) [2-hr] [skin][3]
IDLH (Immediate danger)
 Ca [15 ppm][3]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Phenylhydrazine is the chemical compound with the formula C6H5NHNH2. It is often abbreviated as PhNHNH2. It is also found in edible mushrooms.[5]

YouTube Encyclopedic

  • 1/5
    Views:
    6 468
    222 206
    52 133
    285 213
    1 170
  • Homebrewing phenylhydrazine
  • How to Freebase (Phenylhydrazine HCl as an example)
  • Making Phenylhydrazine (Skatole precursor)
  • Anhydrous Hydrazine: A Powerful but Extremely Dangerous High-Energy Rocket Fuel
  • Detection of Ketonic Functional Group by Phenyl Hydrazine test

Transcription

Properties

Phenylhydrazine forms monoclinic prisms that melt to an oil around room temperature which may turn yellow to dark red upon exposure to air.[1] Phenylhydrazine is miscible with ethanol, diethyl ether, chloroform and benzene. It is sparingly soluble in water.

Preparation

Phenylhydrazine is prepared by reacting aniline with sodium nitrite in the presence of hydrogen chloride to form the diazonium salt, which is subsequently reduced using sodium sulfite in the presence of sodium hydroxide to form the final product.[6]

History

Phenylhydrazine was the first hydrazine derivative characterized, reported by Hermann Emil Fischer in 1875.[7][8] He prepared it by reduction of a phenyl diazonium salt using sulfite salts. Fischer used phenylhydrazine to characterize sugars via formation of hydrazones known as osazones with the sugar aldehyde. He also demonstrated in this first paper many of the key properties recognized for hydrazines.

Uses

Phenylhydrazine is used to prepare indoles by the Fischer indole synthesis, which are intermediates in the synthesis of various dyes and pharmaceuticals.

Phenylhydrazine is used to form phenylhydrazones of natural mixtures of simple sugars in order to render the differing sugars easily separable from each other.[9]

This molecule is also used to induce acute hemolytic anemia in animal models.

Safety

Exposure to phenylhydrazine may cause contact dermatitis, hemolytic anemia, and liver damage.[1]

References

  1. ^ a b c Merck Index, 11th Edition, 7264.
  2. ^ Pure component properties
  3. ^ a b c d e f g NIOSH Pocket Guide to Chemical Hazards. "#0499". National Institute for Occupational Safety and Health (NIOSH).
  4. ^ "Phenylhydrazine". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).
  5. ^ Andersson, H. C.; Gry, Jørn (2004). Phenylhydrazines in the cultivated mushroom (Agaricus bisporus). Nordic Council of Ministers. ISBN 9789289301978.
  6. ^ Merck Index of Chemicals and Drugs, 9th ed. monograph 7098
  7. ^ Nobel Committee Emil Fischer - Biographical
  8. ^ Fischer, E. (1875) "Ueber aromatische Hydrazinverbindungen," Berichte der deutschen chemischen Gesellschaft, 8: 589-594.
  9. ^ Andrew Streitwieser; Clayton Heathcock (1976). Introduction to Organic Chemistry. Macmillan. ISBN 0-02-418010-6.

External links

This page was last edited on 12 April 2024, at 19:42
Basis of this page is in Wikipedia. Text is available under the CC BY-SA 3.0 Unported License. Non-text media are available under their specified licenses. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc. WIKI 2 is an independent company and has no affiliation with Wikimedia Foundation.
Contact WIKI 2
Introduction
Terms of Service
Privacy Policy